摘要
目的 :观察纳洛酮对全麻病人特异性催醒作用。方法 :选择 6 0例用麻醉性镇痛药哌替啶或芬太尼全麻病人 ,分A、B两组。A组 30例术终应用NX0 4mg～ 0 8mg催醒 ;B组 30例应用生理盐水 5ml作对照。结果 :A组RF和VT 治疗后和治疗前比较P <0 0 5 ;RF、VT 治疗后A组和B组比较P <0 0 5。 15min时清醒及拔管A组和B组比较P <0 0 1,A组为B组的 5倍。结论 :NX特异性催醒效应比较强。
Objective To observe the specific wakening effects of naloxone in general anesthesia.Method Sixty patients receiving general anesthesia with narcotic anlgesics,such as pethidine and fentanyl were randomly allocated into two groups:Group A and B (n=30).In group A,0.4mg～0.8mg naloxone was used through the venous round at the end of the operation while in group B.Saline(5ml) was a control.Results In group A,Respiratory frequency (RF) and V T were more significant difference comparing post-treatment with pre-treatment.Group A compared with group B.RF and V T after the treatment were signicantly more different (P<0.05).In fifteen minutes,the time of waking and setting off the endotracheal tube in Group A was more apparently significant difference than in Group B (P<0.01),which was five times of Group B.Conclusion This study provides an evidence that the specific wakening effects of naloxone is more intense.
出处
《吉林医学》
CAS
2002年第5期266-267,共2页
Jilin Medical Journal
