摘要
采用STR基因扫描技术选择D3S1358,υWAWA,FGA,THO1,TPOX,CSF1P0,D5S818,D13S317和D7S820 9种STR基因座,研究我国瑶族人群STR遗传多态性。在瑶族群体中9个STR基因座共检出61个等位基因,其频率分布在0.0054～0.5924,平均杂合度为0.7357,多态信息量为0.6887,累积个体识别率为2.02×10-10,非父排除率为0.9999。结果表明,在人类遗传学、法学科等领域建立本民族本地区遗传学资料是十分重要和必不可少的。
Genetic polymorphism of nine STR loci was investigated from a Chinese Yao population based on STR Ge-nescan. Sixty one alleles was determined for 9 loci,such as D3S1358 ,vWA,FGA, THO1 , TPOX,CSF1PO ,D5S818 , D13S317 and D7S820 with their frequencies 0. 0054 - 0. 5924. The average heterozygosity(H) was 0. 7357, polymorphism information content(PJC) was 0. 6887 ,the accumulative discrimination power(DP) was 2. 02 X 10-10 and the probability of paternity exclusion (PPE) was 0. 9999. These results suggested that the nine STR loci are very useful for human identification,such as analyzing forensic casework,establishing DNA databases,processing paternity test and studying gene natural resources.
出处
《遗传》
CAS
CSCD
北大核心
2002年第5期537-538,共2页
Hereditas（Beijing)
基金
国家自然科学基金(39970401)资助项目
