摘要
本研究采用~3H—TdR释放试验,动态地观察了经SAV或(和)CPV作用后带瘤小鼠小鼠腹腔巨噬细胞细胞毒效应。结果表明,这两种生物制剂均能使带瘤小鼠的巨噬细胞细胞效应明显增强,通过不同途径给药,效果不尽相同。腹腔给药,其巨噬细胞细胞毒效应峰值出现时间较早。而通过皮下给药,则刺激效应持续时间较长。
In this experiment; we observed the effects of SAV and/or CPV on the activities of peritoneal macrophages of the mice with S_(180) tumor by ~3H—TdR release test in vitro. The results display that the cytotoxic effect of the macrophages frovm the mice treated by SAV and CPV on the S_(180) tumor cells in vitro Were superior to that of SAV or CPV alone. Both of intraperitoneal and supcutaneous injection SAV and CPV could promote the cytotoxic action of the macrophage. The peak value of cytotoxic action of the macrophage with intraperitoneal injection was earlier than that with subcutaneons injection, but the latter was mantained longer than the former.
出处
《合肥医学院学报》
1991年第1期21-23,共3页
Journal of Zunyi Medical University
关键词
肉瘤180
葡萄球菌菌苗
巨噬细胞
staphylococcus aureus vaccine
corynebacterium pawum
vaccine
S_180 macrophage
mice
