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膳食抗氧化剂对老年性白内障的作用

Effect of Meal Antioxidant on the Aged Cataract
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摘要 [目的 ]观察膳食抗氧化剂对老年性白内障的影响。[方法 ]选择潍坊市 30名 60~ 75岁健康志愿者 (A组 )与 30名老年性白内障患者 (B组 )。对 B组人群进行 1 5个月的膳食营养指导 ,于营养干预前后 ,通过 7日询问法调查两组人群膳食中抗氧化剂的摄入量 ,检测血清谷胱甘肽过氧化物酶及视力等。 [结果 ]营养干预前 B组膳食抗氧化剂每日摄入量、血液抗氧化酶活力明显低于 A组 P <0 .0 1 )。营养干预后 B组视黄醇当量、维生素 E、维生素 C、硒的每日摄入量明显增加 ,血清中超氧化物歧化酶与谷胱甘肽过氧化物酶活性、血清硒含量明显升高 ,血清脂质过氧化产物丙二醛含量显著降低 P <0 .0 1 ) ;视力下降得到控制。[结论 ]膳食抗氧化剂的摄入量不足可能与老年性白内障有一定关系 。 Objective\]To observe the effects of meal antioxidant on the aged cataract \To choose 30 health volunteers ( group A) and 30 aged cataract sufferers ( group B ) among the 60 75 year old population Group B were given nutrition diet guidance for 15 months Before and after nutrition intervention,by 7 days meal inquisition ,the intakes of meal antioxidant in two groups were investigated Serum GSH PX , eyesight and so on in two groups were tested \Before nutrition intervention ,the daily meal antioxidant intakes and blood antioxidant enzyme activities were obviously lower in group B than in group A (P<0 01) After nutrition intervention, the daily intakes of vitamin A, vitamin E, vitamin C and element Se in group B obviously increased;serum SOD and GSH PX activities with the content of serum Se in group B markedly increased; in addition, molondiadehyde(MDA=content in group B was effectively lower﹙P<0 01) Moreover, in group B eyesight drop was controlled \[Conclusions\]The insufficient intake of meal antioxidant was related to the aged cataract The development of the aged cataract can be controlled by the increase in the intake of meal antioxidant
机构地区 潍坊医学院
出处 《预防医学文献信息》 2002年第5期513-514,共2页 Liferatue and Information On Preventine Medicine
关键词 膳食 抗氧化剂 老年性白内障 营养干预 脂质过氧化 aged cataract nutrition intervention lipid peroxidation
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