摘要
本文测定56例头颈肿瘤患者血清唾液酸基转移酶(?)、唾液酸(SA)、a_(1)—抗胰蛋白酶(a_(1)—AT)和a_(1)—酸性糖蛋白(a_(1)—AGP)含量。结果发现:ST对治疗前肿瘤有无转移的诊断具有显著意义。a_(1)—AT诊断治疗后复发的灵敏度较高,同时检测ST、SA、a_(1)—AT和a_(1)—AGP可提高诊断灵敏度。对治疗后未复发的诊断,以ST的灵敏度最高,同时检测a_(1)—AT、SA和SA、a_(1)—AT,a_(3)—AGP可达到与ST相同的灵敏度。
Concentrations of sialyltransferawe(ST) >sialic acid (SA), a1-antitrypsin(a1-AT) and a1-acid glyco-proteins(a1-AGP) were determined in serum from 56 Patients with head and neck tumor. Our results demonstrated : ST is highly sensitive for diagnosis of metastases in pretreated patients with cancer. a1-AT has higher sensitivity to find patients who develop recurrent tumor after cure. However, combined analysis of ST, SA, a1 -AT and a1-AGP further improved the diagnostic sensitivities. ST is the most sensitive marker for diagnosis of nonrecurrence after cure, but combined analysis of SA ,a1-AT and a1-AGP were as same sensitive as ST.
出处
《重庆医药》
CSCD
1991年第6期326-328,共3页
关键词
头颈肿瘤
唾液酸基转移酶
急相蛋白
head and neck tumor sialyltrasrnsterase acute phase proteins
