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自体腹水浓缩回输治疗肝硬化腹水的疗效评价及机制探讨 被引量:26

THE EVALUATION AND MECHANISM OF THE , EFFECTS OF ULTRAFILTRATION AND REINFUSION OF THE ASCITIC FLUID IN CIRRHOTIC PATIENTS WTIH ASCIETS
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摘要 23例肝硬化合并张力性腹水分组进行自体腹水超滤浓缩回输静脉(A-V)及回输腹腔(A-P)治疗.二组病人近期临床观察结果均有明显改善,血清白蛋白、内生肌酐清除率及尿钠排出明显增加(P<0.01),肾素、血管紧张素Ⅱ、醛固酮浓度均下降(P<0.05~0.01).A-P治疗且可适用于某些不适于A-V疗法的对象.治疗后RAAS的抑制及钠代谢的改变。 Twenty three patients suffering from liver cirrhosis with intensive ascites were divided into two groups and treated by ultrafiltration and intravenous or intraperito-neal reinfusion respectively. The results in both groups revealed definite clinical amelioration, biochemical improvement in serum albumin level and endogenous crea-tinine clearance rate and urine sodium output as well as the plasma levels of RAAS-reduction during short-term observation. In certain cases the method of intraperi-toneal reinfusion revealed as an alternative when they were unsuitable to the treatment of intravenous reinfusion. It is suggested that the interference in sodium metabolism and RAAS might participate in the mechanism of the effects of ultrafiltration of ascites and reinfusion
作者 杨晋辉 钮振
出处 《重庆医科大学学报》 CAS CSCD 1991年第3期208-212,共5页 Journal of Chongqing Medical University
关键词 肝硬变 腹水 超滤 回输 Ultrafiltration Liver cirrhosis Asciies Renin-angiotensin-aldosterone system
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