摘要
目的 :研究丹参、钙剂联合用药预防妊高征的发生。方法 :应用 MP妊高征监测系统对 76 4例 2 0～ 2 8孕周妇女进行预测妊高征 ,筛选出妊高征高危人群 84例 ,随机分为预防组 42例 ,口服复方丹参 4片 ,每日二次 ,钙尔奇— D12 0 0 mg,每日一次至分娩。安慰组 42例 ,口服维生素 C10 0 m g,每日三次至分娩。观察两组妊高征的发生率、服药前后血液动力学变化、分娩情况和新生儿情况。结论 :预防组妊高征 3例 ,发生率为 7.14% ,无重度 ;安慰组发生 12例 ,发生率为 2 8.5 7%。其中轻度 7例 ,重度 2例 ,两组有显著性差异 (P<0 .0 0 1)。两组服药前后血流动力学指标预防组无明显变化 ,安慰组变化显著 (P<0 .0 1)。预防组新生儿体重 336 7± 32 8.6克 ,安慰组新生儿体重 30 5 7± 2 37.2克 ,两组相比差异显著 (P<0 .0 5 )。结论 :对妊高征高危人群进行预防性补钙及口服丹参能有效降低妊高征的发生 。
Objective:To work on how to prevent pregnancy induced hypertension(PIH) by taking Danshen and calcium.Methods:With MP PIH monitoring system,we watched 764 cases of 20-28 pregnant weeks,and selected 84 of them who are anticipated to be more liable to PIH.Then we devided these 84 cases into 2 groups randomly,42 for each.In preventing group,the pregnants took Dansen compound 4 pills twice and calcium pills 1200mg once every day until parturition.In control group,vitaimin C vas used for 100mg 3 times every day until parturition.We reviewed PIH rate,fluctuations in blood dynamics before and after taking medicine,the parturition,and the newborns in each group.Results:in preventing group,we found 3 cases of PIH with rate of 7 14%,no severe PIH.In control group,we found 12 PIH,including 7 mild and 2 severe,the rate was 28 57% in sharp contrast.In preventing group,the changes of blood dynamics were consistent consistent before and after taking medicine,while in control group,they varied considerably.The newborn weight in preventing group was heavier than that in control group.(33 67±328 6g vs 3057±237 2g).Conclusions:This study has demonstrated that red rooted salvia and calcium are effective in preventing PIH and improving the health of pregnant women and newborns.
出处
《现代预防医学》
CAS
2000年第3期384-385,389,共3页
Modern Preventive Medicine
基金
舟山市医学科技进步奖
关键词
复方丹参
钙
妊高征
预防
Danshen compound
Calcium
Pregnancy induced hypertension
