摘要
目的 :把握常见临床感染菌的种类、比率和药物敏感性。方法 :在统一规范细菌培养鉴定和药敏试验材料与方法的基础上 ,对凉山州一医院 1996～ 1998年三年的相关资料进行统计分析。结果 :细菌分离率 ,革兰氏阳性球菌年均19.5 3% ,阴性杆菌年均 5 0 .88% ,深部真菌年均 2 8.12 % ,其余年均 1.48% ;致病菌年均 16 .2 1% ,内源性“正常菌群”和外环境“非致病菌”年均 83.79%。药物敏感性 ,革兰氏阳性细菌和阴性球菌年均敏感率≤ 30 %的药物从低至高依次为青霉素 G、复方新诺明、红霉素、四环素、苯唑青霉素和氨苄青霉素 ,敏感率≥ 6 0 %的药物从高至低依次为万古霉素、丁胺卡那和利复平 ;革兰氏阴性杆菌年均敏感率≤ 6 0 %的药物从低至高依次为利复平、复方新诺明和氨苄青霉素 ,敏感率≥ 6 0 %的药物从高至低依次为丁胺卡那、头孢三嗪、环丙沙星、头孢哌酮、头孢噻肟、氧氟沙星和诺氟沙星。结论 :临床感染菌以革兰氏阴性杆菌和深部真菌多见 ,且以内源性“正常菌群”和外环境“非致病菌”为主 ;耐药株多 ,耐药谱广 ;
Objective:To grasp the kinds、rate and susceptibility of commenly clinical infective bacteria.Methods:In base of unifing and formulating materials and methodes of bacteria cultiveted、evaluated and antimicrobial susceptibility testing,analysed the relevant data of Liangshans first hospital during 1996～1998.it showed that:the rate of gram positiv cocci is 19 53%(pro.year),gram negativ bacilli is 50 88%,fungus in deep is 28 12%,and the others posses 1 48%,pathogen is 16 21%,endogenous normal microbiota and exogenous nonpathogen are 83 79%.Rate of antimicrobial susceptibility:the drugs against gram positive cocci and gram negative bacilli are in ordinal penicillin G、SMZ TMP、erythromycin、tetracycline、oxacillin and ampicillin(rate≤30%),vancomycin、amikacin and rifampin(tate≥60%);the drugs afainst gram negative bacilli are rifampin、SMZ-TMP and ampicillin(rate≤30%),amikacin、ceftriaxone、ciprofloxacin、cefoperazone、cefotaxime、ofloxacin and norfloxacin(rate≥60%).Result:The most clinical infective bicteria are gram negative bacilli and fungus in deep,the endogenous normal microbiota and exogenous nonpathogen are mainly,the kinds and ranges of resistance to drugs are there in plenty.The scientific management for hospital infection and antimicrobial used must be strengthened.
出处
《现代预防医学》
CAS
2000年第3期337-339,350,共4页
Modern Preventive Medicine
