摘要
将成年小白鼠通过人为的骨折与烧伤造成"外伤及肾"的动物模型。实验结果发现模型组小白鼠睾丸有退行性变化,精子成熟过程受阻;电镜下又见脑垂体促性腺激素细胞胞浆内颗粒减少、核固缩及空泡变性和出血等现象,说明急病及肾在病理形态上的改变主要表现在垂体—性腺轴上,这在肾本质实验研究方面是一个新的进展。
An experimental study using adult Kunming male mice was designed to observe the Shen reaction to trauma(bone fracture and burn).It was shown that the mice testes of the experimental groups were degenerated and the spermatogenesis disturbed.Under the electron microscope,the granules reduction,pyknosis,vesicular degeneration in the plasma of gonadotrophs and hemorrhage were found.It was revealed that the pathological changes of Shen by trauma were mainly attacked on the adenohypophysis-gonadal axis.According to the results of this experimental study,the Shen in the hypothesis of 'trauma hurts Shen' should be related to testes and ovaries(gonadal organs).
关键词
骨折
烧伤
肾
睾丸
bone fracture
burn
Shen
testes
