摘要
选用40只日本大耳白兔,静脉注射戊巴比妥钠造成实验性充血性心力衰竭,以中药复方注射液心复宁Ⅳ号治疗,观察心衰前、心衰时及治疗后血浆心钠素浓度,心房组织心钠素含量变化。结果表明,心复宁Ⅳ号可使心衰兔心钠素水平升高,说明心复宁Ⅳ号能够改善心脏内分泌功能,对心力衰竭具有可靠疗效。
By use of pentobarbital sodium to produce experimental congestive heart failure (CHF) in 40 rabbits,they were treated with Xin-Fu-Ning IV (XFN IV),the plasma atrial natriuretic factor(ANF) levels and atrial tissue ANF levels of rabbits were measured.The results showed that XFN IV had elevated ANF levels of the rabbits with CHF.It showed that XFN IV could improve endocrine function of heart,and it also-showed good curative effect on CHF.
关键词
心复宁IV号
心力衰竭
心钠素
Xin-Fu-Ning N
strophanthin K
atrial natriuretic factor
experimental heart failure