摘要
本文报道治疗组301例支气管哮喘应用卡虎素;对照组30例应用死卡介苗,以3个月为1疗程。治疗后近期有效率两组分别为81.40%与80%;远期有效率分别为44.83%与42.31%,两组差异无统计学意义。疗效与病型、病情关系明显。治疗后患者淋巴细胞绝对值、IgG、IgA 升高,植物血凝素(PHA)与 OT 试验增强。而 C_3明显下降,提示卡虎素可提高机体的细胞免疫与体液免疫。治程中临床与实验室检查均未发现异常。
301 cases of bronchial asthma(BA)in observation group were treated by Kahusu[each tablet contained 50 mg heat-killed BCG and 50 mg Huercaosu(虎耳草素)]with the oral administration 1 tablet each time,3 times each week and 30 cases of BA in control group were treated by heat-killed BCG(each tablet contained 100mg)with the oral administration 1 tablet 3 times each week.Each treatment course was 3 months in both groups.After 1 year's treatment the effective rates of these 2 groups were 81.40% and 80% respectively,and during 2 years follow-up the effective rates of both groups were 44.83% and 42.31% respectively.It was not statistically significant between both groups. The therapeutic effects were associate with the type and the condition of BA.Laboratory examina- tion showed that IgG,IgA value increased,PHA and OT test strengthened and C_3.lowered clearly. It indicated that both cellular and humoral immunity had been strengthened and inflammation had beenresolved.In the course of treatment no side effect had been found.
关键词
卡虎素
哮喘
免疫制剂
Kahusu
bronchial asthma
immunity drug
dead BCG
Huercaosu
