摘要
用免疫组织化学方法及组织化学特殊染色法观察35例嗜酸性淋巴肉芽肿病变组织中的lgE、IgA、IgM、IgG抗体和肥大细胞,结果表明,病变组织中IgE明显增多,主要分布在淋巴滤泡生发中心内及生发中心外浆细胞内,肥大细胞大量增生,其分布及数量与一般的慢性炎症组织明显不同。
Immuno-histochemistry and special histochemistry staining were used to observe the quantity and distribution of IgE, IgA, IgM, and IgG antibodies as well as mast cell in the tissues of 35 cases with eosinophilic lymphogranuloma(ELG). The results indicated that IgE-positive reactions were found in most of the germinal centers. Furthermore, some cells with IgE-positive reactions in their membranes were also demonstrated. Mast cells' hyperplasia was seen. Their quantity and distribution in ELG were obviously different from that in other unspecific chronic inflammation.
It was suggeted that Type I allergy might be the main etiopathology of ELG. The lymphoid proliferation, Mast cell hyperplasia and increase of IgE, as mentioned above, were the manifestation of Type I allergy at all.
出处
《中山医科大学学报》
CSCD
1991年第2期130-132,共3页
Academic Journal of Sun Yat-sen University of Medical Sciences
关键词
淋巴肉芽肿
嗜酸性
免疫病理学
Eosinophilic lymphogranuloma (ELG) Immuno-histochemistry IgE Mast cell Type I allergy
