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肺鳞癌细胞的计算机诊断研究 被引量:1

Computer-aided Cytologieal Diagnosia ot Squamoug.Carcinoma of Lung
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摘要 本文选择肺瞬癌、瞬状上皮增生各30例,另选30例正常瞬状上皮中层细胞作对照,上述鳞癌、增生、正常细胞各选300个。每个细胞测量胞体最大直径(DC)、胞核最大直径(DN)、胞核胞体最大直径之比(N/C)、胞核形状(NS)、核仁与胞核最大直径之比(n/N)和核染色质分布(CD)6项指标。从每个实际数算出概率和指数值排成矩阵。使用BASIC语言编制程序将各指数值输入AppleI型微机。用65例确诊为肺瞬癌的细胞涂片,人工测量每个癌细胞上述6项指标,将测得的各数值也输入上述微机,验证原输入微机内的指数值(数学模型)的准确性。检查结果显示准确性最高达90~96%。 Three hundred cells from 30 cases were selected respectirely fromsquamous carcinoma cells,hyperplastic squamous cells and normal squamous cells of themiddle layer in Iung.We measured six parameters above cells,the diameter of thecells(DC),the diameter of the nuclel(DN),the nuclear-cytoplasmlc ratio(N/C),the shape of nuclei(NS),the nucleolar-nuclear ratlo(n/N),and the distributionof the nuclear chromatin(CD).The probability and exponential value were computedfrom each actual value.The operatlve order was made from the exponential valueswith BASIC word and transformed into the Apple II microcomputer.Using the cellsfrom 65 cases of squamous carcinoma of the lung to examlne the mathematic model,we found that the accuracy of diagnosis was highly reached to 90-96%.The studyshowed that the method was reliable and had an advantage of high diagnostic speed.
作者 彭善友 形寿富 王圣基 肖作均 褚岚 何平 Peng Shan-you(First Hospital,Hubei Medioal Colege)
出处 《中华物理医学杂志》 CAS CSCD 1991年第1期43-45,共3页 Chinese Journal of Physical Medicine and Rehabilitation
关键词 计算机 鳞状细胞癌 肺脏 computer squamous cell carcinomar lung
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  • 1彭善友 王圣基 等.微型电子计算机在肺癌细胞学诊断上的试用[J].中华病理学杂志,1987,16(3):170-170.

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