摘要
对1446名接触氯丁二烯男工和1127名对照男工的生殖结局进行了回顾性队列研究。使用SAS程序包,采用X^2检验和非条件Logistic回归分析方法,结果表明,氯丁二烯作业男工妻子的自然流产发生率(5.52%)显著高于对照组(3.52%),P<0.01。控制混杂因素后的相对危险度为1.29,95%可信限为1.09～1.53。其自然流产率的显著增高主要表现于早期自然流产率的显著增高。但本研究未发现男工接触氯丁二烯能使不孕、过期产、早产、死产、低体重儿、新生儿死亡和围产儿死亡等的发生率显著增高。
A retrospective cohort study on the reproduction of 1446 male workers ex-posed to chloroprene vs 1126 non-exposed workers was carried cut,Resultswere analysed by SAS.X^2 tests and non-conditional Logistic regression wereused.Spontaneous abortion occurred in 5.52% of wives of exposed male work-ers vs 3.52% in control (P<0.01).After controlling confounders RR=1.29(95% Cl:1.09—1.53).Spontaneous abortions in exposed group mainly oc-curred in the first trimester of pregnancy.Other parameters of reproductivedamage,such as infertility,premature delivery,congenitalmalformation,infant death,etc.also studied.
出处
《中华劳动卫生职业病杂志》
CAS
CSCD
1991年第4期202-205,共4页
Chinese Journal of Industrial Hygiene and Occupational Diseases
关键词
氯丁二烯
男性
生殖损伤
流行病学
Chloroprene
Male reproductive damage
Spontaneous abortion
