摘要
目的:观察养阴活血复脉汤联合西药治疗慢性心力衰竭(CHF)气阴两虚血瘀证的疗效。方法:筛选本院收治的88例CHF气阴两虚血瘀证老年患者,采取随机数字表法分为对照组和治疗组,每组44例。2组均行常规规范疗法,治疗组加用养阴活血复脉汤。2组连续治疗3月,并随访6月,期间采用多普勒超声心动图仪检测患者的左心室射血分数(LVEF)和左室舒张末期内径(LVEDD)。结果:治疗3月后,治疗组总有效率93.18%,高于对照组的总有效率75.00%,差异有统计学意义(P <0.05)。治疗后,2组LVEF均较治疗前增高,LVEDD均较治疗前下降(P <0.01)。治疗3月、6月和9月,治疗组LVEF高于对照组,LVEDD低于对照组,差异均有统计学意义(P <0.01)。2组均完成6月的随访观察。治疗组再入院率和死亡率分别为13.64%和4.55%,低于对照组的34.09%和22.73%,差异均有统计学意义(P <0.01)。结论:在常规西药基础上加用养阴活血复脉汤治疗CHF气阴两虚血瘀证患者可以改善心功能、减缓疾病进展,提高临床疗效与预后效果。
Objective： To observe the curative effect of Yangyin Huoxue Fumai tang combined with western medicine for chronic heart failure（CNF） with qi-yin deficiency with blood stasis syndrome. Methods：Selected 88 cases of senile patients with CNF with qi-yin deficiency with blood stasis syndrome admitted in our hospital into the control group and the treatment group according to random number table method, 44 cases in each group. The two groups received routine treatment, while the treatment group additionally received Yangyin Huoxue Fumai tang for treatment. The two groups were continuously treated for three months. Followed up patients for six months and detected left ventricular ejection fraction（LVEF） and the left ventricular end-diastolic diameter（LVEDD） of patients by Doppler ultrasound echocardiograph. Results： After three months of treatment, the total effective rate was 93.18% in the treatment group,higher than that of 75.00% in the control group,the difference being significant（P〈0.05）. After treatment,the LVEF in the two groups was increased when compared with that before treatment,while the LVEDD was decreased when compared with that before treatment（P〈0.01）. After three,six and nine months of treatment,LVEF in the treatment group was higher than that in the control group,while the LVEDD was lower than that in the control group,differences being significant（P〈0.01）. Six-month follow-ups in the two groups were all finished. The readmission rate and the mortality rate were 13.64% and 4.55% respectively in the treatment group,lower than those of 34.09% and 22.73% respectively in the control group,differences being significant（P〈0.01）. Conclusion：Based on the western medicine, the additional application of Yangyin Huoxue Fumai tang for CNF with qi-yin deficiency with blood stasis syndrome can improve cardiac function,slow down the development of the disease and improve the clinical effect and prognosis effect of patients.
出处
《新中医》
CAS
2018年第10期49-51,共3页
New Chinese Medicine
关键词
慢性心力衰竭(CHF)
气阴两虚证
血瘀证
中西医结合疗法
养阴活血复脉汤
心功能
Chronic heart failure （CHF）
Qi-yin deficiency syndrome
Blood stasis syndrome
Integrated Chinese andwestern medicine therapy
Yangyin Huoxue Fumai tang
Cardiac function
