摘要
采用2 Hz电针分别对18、20和22月龄大鼠肾俞和足三里进行干预,探讨电针对TGF-β/Smad信号通路的作用,为延缓增龄所致的骨骼肌萎缩提供依据。认为电针干预能够减缓增龄性骨骼肌萎缩的进程,其机制可能与电针干预促进骨骼肌再生和/或后期降低骨骼肌的纤维化有关。
Electroacupuncture by 2 Hz was used respectively for 18 months,20 months and 22 months of rats in this study. The effects of electroacupuncture on the TGF-β/Smad signaling pathway were explored to provide the basis for attenuating age-related skeletal muscle atrophy. We hold that electric acupuncture could attenuate aging-related rat skeletal muscle atrophy by promoting muscle regeneration and/or reducing skeletal muscle fibrosis in the later stage.
作者
虎力
温佩彤
张伟波
高原
寿崟
王晓南
徐平
HU Li;WEN Peitong;ZHANG Weibo;GAO Yuan;SHOU Yin;WANG Xiaonan;XU Ping(Acumox ＆ Tuina College of Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China;Department of Medicine of Emory University,Atlanta,GA 30322)
出处
《中华中医药学刊》
CAS
北大核心
2018年第9期2064-2067,I0001,I0002,共6页
Chinese Archives of Traditional Chinese Medicine
基金
国家自然科学基金青年科学基金项目(81403470)
国家自然科学基金面上项目(81373755)
