摘要
目的探究肝素对紫癜性肾炎的防治效果。方法选取2017年6月~2018年6月收治的52例紫癜性肾炎患儿,将其随机分为对照组与研究组,各26例。对照组采取常规治疗,研究组加用低分子肝素钙。对比两组患儿的肾炎治疗效果以及皮肤紫癜、关节肿痛、腹痛等症状的消失时间。结果研究组皮肤紫癜、关节肿痛、腹痛等症状的消失时间均短于对照组,差异有统计学意义(P<0.05);研究组紫癜性肾炎的治疗总有效率96.15%,高于对照组76.92%,差异有统计学意义(P<0.05)。结论肝素能够改善紫癜性肾炎患儿的临床症状,其对紫癜性肾炎有显著防治效果。
Objective To explore the effect of heparin on the prevention and treatment of purpuric nephritis.Methods A total of 52 children with purpuric nephritis admitted from June 2017 to June 2018 were randomly divided into control group and study group,26 cases each.The control group received routine treatment and the study group received low molecular weight heparin calcium.The effects of nephritis treatment and the disappearance of symptoms such as purpura,joint swelling,and abdominal pain were compared between the two groups.Results The disappearance time of skin purpura,joint swelling and pain,abdominal pain and other symptoms in the study group was shorter than that in the control group,the difference was statistically significant(P〈0.05).The total effective rate of treatment of purpuric nephritis in the study group was 96.15%,which was higher than that in the control group 76.92%,the difference was statistically significant(P〈0.05).Conclusion Heparin can improve the clinical symptoms of children with purpuric nephritis,and it has significant control effect on purpuric nephritis.
作者
秦盼盼
QIN Pan-pan(Department of Nephrology,West China Guang'an HospitaI,Sichuan University,Guangan 638000,Sichuan,China)
出处
《医学信息》
2018年第17期130-131,134,共3页
Journal of Medical Information
关键词
肝素
紫癜性肾炎
防治效果
症状消失时间
Heparin
Purpuric nephritis
Prevention and treatment effect
Symptom disappearance time