摘要
目的:观察督灸治疗对慢性阻塞性肺疾病稳定期肺脾肾亏虚型临床及T细胞亚群的影响。方法:采用随机数字表法将48名患者分为治疗组和对照组,对照组患者予常规西医治疗,治疗组患者在对照组治疗基础上行督灸治疗并观察患者中医症候积分、肺功能、急性加重次数、CD4+、CD8+变化情况。结果:治疗组症候积分下降,差异有统计学意义(P<0.01),且治疗组与对照组治疗后症候积分变化差异有统计学意义(P<0.05)。治疗组患者FEV1、FEV1%、FEV1/FVC%与治疗前比较有所增加,但差异无统计学意义(P>0.05)。两组肺功能检测结果比较,差异均无统计学意义(P>0.05)。治疗一个疗程治疗组患者较对照组急性加重次数减少,差异有统计学意义(P<0.05)。治疗组辅助性T细胞数值(CD4+、CD8+),较前升高,且差异有统计学意义(P<0.05).结论:督灸治疗对慢性阻塞性肺疾病稳定期(肺脾肾亏虚)患者中医证候积分、急性加重次数、T细胞亚群有明显改善作用。
Objective： To observe the clinical effect of Du-moxibustion on stable chronic obstructive pulmonary disease（COPD） of lung, spleen and kidney deficiency syndrome and T cell subsets. Methods： 48 cases of patients were randomly divided into treatment group and control group.The contral group was treated with routine western medicine,while the treatment group was treated with Du-moxibustion on the basis of control group.The changes of TCM syndrome score, pulmonary function, number of acute exacerbation,CD4＋ and CD8＋ of patients were observed. Results： Compared with before treatment： the change difference of syndrome score of patients in control group was not statistically significant （P〉0.05）; the syndrome score in treatment group decreased,the difference was statistically significant （P〈0.01）; and after treatment,the change difference of syndrome score between treatment group and control group was statistically significant（P〈0.05）.Compared with before treatment： FEV1, FEV1% and FEV1/FVC% of patients in treatment group increased a little,but the difference was not statistically significant （P〉 0.05）; the difference of FEV1, FEV1% and FEV1/FVC% in control group was not statistically significant （P〉0.05）. After treatment, the results of detection of pulmonary function （FEV1, FEV1%, FEV1/FVC%） were compared in two groups,the difference was not statistically significant （P〉0.05）.After a course of treatment, through observing the number of acute exacerbation of patients in this course,we found that the number of acute exacerbation of patients in treatment group was less than that in control group,and the difference was statistically significant （P〈0.05）.After treatment, the auxiliary values （CD4＋ and CD8＋ ）of T cells were observed in two groups. The results showed that the change of values in control group was without difference,while the values in treatment group were higher than before treatment and the difference was statistically significant （P〈0.05）.Conclusion： Du-moxibustion can significantly improve TCM syndrome score, number of acute exacerbation and T cell subsets of patients with COPD of lung, spleen and kidney deficiency syndrome.
作者
赵裕沛
黄宝驹
朱益敏
ZHAO Yu-pei;HUANG Bao-jv;ZHU Yi-min(The Second Affiliated Hospital of Nanjing University of Traditional Chinese Medicine,Nanjing,210017,China)
出处
《山西中医》
2018年第9期25-27,共3页
Shanxi Journal of Traditional Chinese Medicine
关键词
慢性阻塞性肺疾病
督灸
肺脾肾亏虚
T细胞亚群
chronic obstructive pulmonary disease
Du-moxibustion
lung spleen and kidney deficiency
T cell subsets
