摘要
目的研究寻常型银屑病患者的生活质量情况与各中医证型的相关因素,为寻常型银屑病的中医整体治疗提供理论依据和治疗思路。方法由一名及以上的中医皮肤科主治医生对101例银屑病患者进行中医辨证,分为血热证、血瘀证和血燥证。采用国际通用的银屑病调查表(PDI)及皮肤病生活质量指数(DLQI)两种量表对患者进行测评,比较各证型组患者两种量表测评总分和各维度分值情况。结果与血热证组比较,血瘀证组DLQI总分、血燥证组PDI总分和DLQI总分较低(P<0.05或P<0.01)。PDI各维度评分显示,除治疗维度外,血热证组与血燥证组其余各维度分值差异均具有统计学意义(P<0.05),血热证组与血瘀证组在日常工作维度的分值差异具有统计学意义(P<0.01)。DLQI各维度评分显示,与血热证组比较,血燥证组的各维度分值较低(P<0.05或P<0.01),血瘀证组的日常生活、工作学习维度的分值较低(P<0.05或P<0.01),血瘀证组与血燥证组的症状感受维度分值差异具有统计学意义(P<0.05)。结论寻常型银屑病患者的中医辨证分型与生活质量存在一定的联系,血热证患者较血瘀证及血燥证患者的生活质量差。
Objective To find the correlation of the quality of life in psoriasis vulgaris patients with varies traditional Chinese medicine（TCM） syndrome differentiation, to provide theoretical evidence and treatment idea for the TCM doctors to take holistic treatment for psoriasis vulgaris patients. Methods Total of 101 cases of psoriasis vulgaris patients were selected and divided into blood heat syndrome group, blood stasis syndrome group and blood dryness syndrome group according to TCM syndrome differentiation by one or more of the dermatologists of TCM. The psoriasis disability index（PDI） and dermatology life quality index（DLQI） were used to evaluate the patients, and the total scores of PDI and DLQI, and the scores of each dimension of PDI and DLQI in each group were compared. Results Compared with the blood heat syndrome group, the total DLQI score in blood stasis syndrome group, the total PDI score and the total DLQI score in blood dryness syndrome group were lower（P〈0.01）. The PDI scores of each dimension showed that, except for the treatment dimension score, the difference of the other dimension scores between the blood heat syndrome group and the blood dryness syndrome group were statistically significant（P〈0.05）. The difference of the daily work dimension score between the blood heat syndrome group and the blood stasis syndrome group was statistically significant（P〈0.01）. The DLQI scores of each dimension showed that, compared with blood heat syndrome group, each dimension scores in blood dryness syndrome group were lower（P〈0.05 or P〈0.01）, the daily life and work learning dimension scores in blood stasis syndrome group were lower（P〈0.05 or P〈0.01）, and the difference of the symptom feeling dimensions score between the blood stasis syndrome group and the blood dryness syndrome group was statistically significant（P〈0.05）. Conclusion The TCM syndrome differentiation in psoriasis vulgaris patients is related with their quality of life. The life quality of the patients with blood heat syndrome is worse than that in blood stasis and blood dryness syndrome patients.
作者
平立
李咏梅
高尚璞
李燕娜
李晓睿
PING Li;LI Yong-mei;GAO Shang-pu;LI Yan-na;LI Xiao-rui(Department of Dermatology,Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200032,Chin)
出处
《世界临床药物》
CAS
2018年第7期475-479,共5页
World Clinical Drug
基金
国家中医药管理局名老中医马绍尧工作室建设项目(编号:LH0206021)
海派中医流派传承研究基地-顾氏外科建设项目(编号:ZY3-CCCX-1-1004)
关键词
银屑病
生活质量
中医证型
psoriasis
quality of life
traditional Chinese medicine syndrome differentiation
