摘要
甲状腺相关眼病(TAO)是一种通常伴有甲状腺功能异常的眼部症状,其治疗是临床的一大难点,需要同时考虑患者主观感受和病情的客观需求。目前主要有基础治疗、药物治疗(激素、免疫抑制剂、生长抑素及类似物、球后放疗等)、手术治疗。药物治疗适用于活动性TAO患者,目前首选的是激素类;手术治疗则可用于药物治疗不能控制的视力损害,以及为了追求更好疗效和外观,手术方式以眼眶减压术、眼肌手术、眼睑手术为主。各种治疗手段均存在着不同的优缺点。
Thyroid associated ophthalmopathy（TAO） is an eye symptom that is usually associated with abnormal thyroid function,and the treatment is a major clinical difficulty because the subjective and objective needs of the patients should be considered simultaneously.Treatment options for TAO can be grouped into adjuvant,medical（steroids,immunosuppressive therapies,somatostatin analogues,orbital radiotherapy etc.）,and surgical therapies.Medical therapy is applicable to patients with active hyperthyroidism and steroids is the first choice,while surgical interventions can be implemented in cases where the threat to vision cannot be controlled with medical treatment,and in cases with inactive disease in order to protect function and improve appearance.Orbital decompression,ocular muscle surgery and blepharoplasty are the main methods of operation.All kinds of treatments have different advantages and disadvantages.
作者
郭娅琼
李竞
GUO Yaqiong;LI Jing(Department of Endocrinology,Renmin Hospital of Wuhan University,Wuhan 430060,China)
出处
《医学综述》
2018年第11期2201-2205,共5页
Medical Recapitulate
关键词
甲状腺相关眼病
激素
免疫抑制剂
手术治疗
Thyroid associated ophthalmopathy
Steroids
Immunosuppressant
Surgical therapies
