摘要
目的探讨多次行内镜下逆行胰胆管造影(ERCP)对儿童慢性胰腺炎患者治疗的有效性和安全性。方法回顾性分析2008年1月至2017年12月在首都医科大学附属北京友谊医院多次(≥2次)行ERCP治疗慢性胰腺炎的儿童患者(首诊年龄≤14岁)的临床资料,并对其作统计分析。结果共入选患者18例,其中男性10例,女性8例,年龄5~13岁。患儿的主要症状为腹痛(18/18,100%),18例患者共进行治疗性ERCP 54人次,插管成功率为96.3%(52/54),置入胰管支架治疗47人次,第1次ERCP治疗后腹痛缓解率为72.2%(13/18)。术后胰腺炎的发生率为7.4%(4/54),无穿孔、出血等并发症发生。随访6~49个月,更换胰管支架的时间为1~11个月,更换次数2~6次,其中4例已完全拔除胰管支架。结论多次行ERCP对于治疗儿童慢性胰腺炎是安全有效的方法。
Objective To investigate the safety and efficiency of multiple ERCPs on chronic pancreatitis in children. Methods Retrospective review was performed in this study from January 2008 to December 2017. The pediatric patients（ no more than 14 years old）,who were diagnosed as chronic pancreatitis and performed ERCP more than twice in Beijing Friendship Hospital,Capital Medical University,were enrolled in this study. All the clinical data was collected and analyzed. Results Eighteen children,including ten males and eight females,aged from 5 to 13 years old,were enrolled in this study. The main symptom was abdominal pain（ 18/18,100%）. A total of 54 ERCP procedures were performed on these children,which included 47 pancreatic duct stenting. The cannulation success rate was 96. 3%（ 52/54）. After the first ERCP,72. 2%（ 13/18） of the patients had a pain completely remission. The total complication rate of post-ERCP pancreatitis was 7. 4%（ 4/54）,none perforation and bleeding occured. During the follow-up period ranged from 6 to 49 months,the interval period for changing stent was 1-11 months with changing times from 2 to 6. Conclusion Multiple ERCPs in pediatric chronic pancreatitis patients were safe and effective.
作者
焦月
冀明
李巍
刘缚琨
JIAO Yue;JI Ming;LI Wei(Department of Gastroenterology,Beijing Friendship Hospital,Capital Medical University,Beijing Digestive Disease Center,National Clinical Research Center for Digestive Disease,Beijing 100050,China.)
出处
《临床和实验医学杂志》
2018年第16期1787-1790,共4页
Journal of Clinical and Experimental Medicine
基金
国家科技部科技支撑项目(编号:2015BAI13B09)
关键词
儿童
慢性胰腺炎
内镜下逆行胰胆管造影
Children
Chronic pancreatitis
Endoscopic retrograde cholangiopanereatographyde
