摘要
目的探讨ERCP后并发胰腺炎的影响因素。方法回顾性分析2 824例行ERCP患者的有关临床资料。单因素变量分析术中胰管显影、胆管插管失败、EST、胆管扩张、黄疸、胰腺炎病史、性别、年龄等方面的影响因素。结果胰管显影、胆管插管失败、无黄疸、胰腺炎病史、中青年龄均使ERCP后胰腺炎发生率升高(P<0.01),而胆管扩张、EST、性别均未明显影响行ERCP后胰腺炎的发生率(P>0.05)。结论 ERCP后并发胰腺炎的影响因素中,胰管显影、胆管插管失败、无阻塞性黄胆、胰腺炎病史、中青年龄等均为ERCP后胰腺炎的高危因素,而胆管扩张、性别等不是ERCP后胰腺炎的高危因素。EST的规范化可明显减少胰腺炎的发生率。
Objective To investigate potential risk factors for post-endoscopic retrograde cholangiopancreatography pancreatitis（PEP）.Methods Clinical data of 2 824 patients underwent endoscopic retrograde cholangiopancreatography（ERCP） were analyzed retrospectively.Data including pancreatic duct opacification,failure of bile duct cannulation,endoscopic sphincterotomy（EST）,bile duct dilatation,jaundice,history of pancreatitis,gender and age were collected and analyzed using univariate analysis.Results The incidence of PEP was significant higher in patients with pancreatic duct opacification,failure of bile duct cannulation,nonobstructive jaundice,history of pancreatitis,young or middle age（P0.01）.Bile duct dilatation,EST and sex did not affect the incidence of PEP（P0.05）.Conclusion Pancreatic duct opacification,failure of bile duct cannulation,EST,nonobstructive jaundice,history of pancreatitis and young or middle age are risk factors related to PEP.However,bile duct dilatation and sex are not risk factors associated with PEP.Thus,further stratification of ERCP patients and standardization of EST procedure can reduce the rate of PEP.
出处
《肝胆胰外科杂志》
CAS
2010年第5期389-391,394,共4页
Journal of Hepatopancreatobiliary Surgery
关键词
ERCP
胰腺炎
影响因素
预防
endoscopic retrograde cholangiopancreatography pancreatitis risk factor prevention
