摘要
目的:探讨儿童腹部神经母细胞瘤(NB)和节细胞神经母细胞瘤(GNB)的CT表现特征及CT在两者诊断及鉴别诊断中的价值。方法:回顾性分析经病理证实的118例儿童腹部NB和31例GNB的临床、病理及CT资料。结果:NB患者的平均发病年龄为29.1个月,GNB患者的平均发病年龄为41.7个月。118例NB患者中,64例(54.2%)出现远处转移,80例(68.0%)肿瘤表现为形态不规则肿块,60例(50.8%)肿瘤跨越中线生长,62例(52.6%)肿瘤边界不清晰,78例(66.0%)可见肿瘤内钙化,形态为粗大、不定型钙化,101例(86.0%)肿瘤增强后呈不均匀强化,85例(72.0%)包绕周围血管生长,27例(22.9%)肿瘤侵犯邻近组织器官。31例GNB患者中,4例(12.9%)出现远处转移,28例(90.0%)肿瘤边界清晰,25例(80.0%)表现为形态规则肿块,21例(68%)可见肿瘤内钙化,4例(12.9%)肿瘤包绕血管生长。结论:NB与GNB的CT表现有一定差异,NB多表现为边界不清、形态不规则肿块,跨越中线生长,包埋邻近血管,粗大不定型钙化是其特征性CT表现,增强扫描呈明显不均匀强化,常伴局部脏器浸润。GNB多呈形态规则、边界清晰肿块,对周围大血管及组织器官以推移为主。
Objective：To explore the value of CT findings in the diagnosis and differential diagnosis between abdominal neuroblastoma（NB）and ganglioneuroblstoma（GNB）in children.Methods：Clinical,pathological and CT data of 118 NBs and 31 GNBs,confirmed by pathology,were analyzed retrospectively.Results：The mean age of NB was 29.1 months,while GNB was 41.7 months.Of all the118 NB patients,64（54.2%）had distant metastasis when initially attended;80（68.0%）had irregular sharp and ill-defined edge,60（50.8%）grew across the midline.78（66%）had coarse calcifications.Post-contrast CT showed uneven mild or moderate enhancement in 101 cases,wrapped vessels in 85 cases,adjacent tissue and organ invasion in 27 cases.Among the 31 GNBs,4 cases had distant metastasis when initially attended,28 had well-defined edge and 25 were of regular shape.Conclusions：The CT features of NB differed from those of GNB.NB tends to be an ill-defined mass with coarse calcifications,growing cross the midline,and encasing vessels;conversely GNB frequently seems to be well-defined mass with regular shape and vessels displacement.
作者
贺文广
任刚
蔡嵘
唐文
倪婧
陈健
HE Wen-guang,REN Gang,CAI Rong(Department of Radiology,Xinhua Hospital,Shanghai Jiaotong University School of Medicine,Shanghai200092 , Chin)
出处
《放射学实践》
北大核心
2018年第5期493-497,共5页
Radiologic Practice
基金
上海交通大学医学院科研基金(Grants No.09XJ21013)
上海市卫生局科研基金(Grants No.2010029and2010057)
上海市科委科研基金(Grants No.124119a0300)
上海市教委科研基金(Grants No.12Y2034)
