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罗哌卡因复合舒芬太尼硬膜外麻醉对分娩产妇疼痛程度及应激状态的影响 被引量:23

Effects of ropivacaine combined with sufentanil on epidural anesthesia and maternal pain and stress
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摘要 目的研究讨论罗哌卡因复合舒芬太尼硬膜外麻醉对分娩产妇疼痛程度及应激状态的影响。方法选取2015年3月—2016年3月正常生产的200例产妇,按照随机数字表达法分为观察组(罗哌卡因复合舒芬太尼组)和对照组(单独使用罗哌卡因组),每组各100例。比较2组产妇用药后药物的起效时间、首剂量持续时间以及产程时间和2组不同产程产妇的疼痛评分,及不良妊娠结局(器械助产、剖宫产、新生儿窒息、产后出血)的发生率,对比2组麻醉药物对分娩产妇的疼痛程度和应激状态的影响。结果结果显示,观察组药物注射起效时间较对照组低,首剂量持续时间较对照组长(P<0.05);观察组能有效缩短第一、二产程时间,VAS评分低于对照组,2组比较差异有统计学意义(P<0.05),但对第三产程影响不大,2组比较差异无统计学意义(P>0.05);2组器械助产、剖宫产和产后出血发生率比较,差异有统计学意义。结论罗哌卡因复合舒芬太尼硬膜外麻能有效减轻分娩产妇的疼痛程度,缓解产妇的应激状态,减少不良妊娠结局发生率,可以在临床中推广和使用。 Objective To investigate the effect of ropivacaine combined with sufentanil on epidural anesthesia and maternal pain and stress among puerperants. Methods Two hundred normal puerperants admitted to our hospital between March 2015 to March 2016 were selected and randomly divided into the observation group(ropivacaine combined with sufentanil group) and control group(ropivacaine alone group), with 100 cases in each. The onset time of drugs, duration of the first dose, duration of delivery, pain scores, incidence of adverse pregnancy outcomes(instrumental delivery, cesarean section, neonatal asphyxia, and postpartum hemorrhage) and levels of stress were compared between the two groups. Results The onset time of drug injection in the observation group was shorter than that in the control group, while the duration of the first dose was longer than that of the control group(P〈0.05).The first and second stages of labor were effectively shortened in the observation group, and the VAS score was lower than in the control group, so there was significant difference between the two groups(P〈0.05). However, there was little effect on the third stage of labor, and there was no significant difference between the two groups(P〉0.05). The difference in the incidence of instrumental delivery, cesarean section and postpartum hemorrhage was statistically significant between the two groups. Conclusion Ropivacaine combined with sufentanil can effectively reduce the pain of maternal delivery, relieve the stress state of puerperants, reduce the incidence of adverse pregnancy outcomes,suggesting that this approach should be popularized in clinical practice.
作者 唐斌 余德 TANG Bin;YU De(Department of Anesthesiology, Huangshi Maternal and Children's Health Hospital, Edong Health Care Group, Huangshi Hubei 435000, Chin)
出处 《空军医学杂志》 2018年第2期104-106,114,共4页 Medical Journal of Air Force
关键词 罗哌卡因 舒芬太尼 疼痛程度 应激状态 ropivacaine sufentanil pain degree stress state
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