摘要
目的探讨吲哚菁绿排泄试验、血清前白蛋白、Child-Pugh评分指导肝脏切除的效果。方法对80例行肝脏切除的患者术前常规行Child-Pugh评分,检测吲哚菁绿15min排泄率(ICGR15)、血清前白蛋白(PA);患者根据ChildPugh评分A、B级分为A、B组;根据ICGR15分为ICGA组(ICGR15<10%)、ICGB组(10%<ICGR15<20%)和ICG C组(ICGR15≥20%);术后患者分为肝功能正常组(G组)、轻度肝功能不全组(M组)、重度肝功能不全组(S组),比较各组患者的差异。结果不同Child-Pugh评分组及ICGR15分组患者的术后肝功能代偿情况差异有统计学意义(P<0.01)。不同术后肝功能代偿患者(G、M、S组)的Child-Pugh评分、ICGR15及PA水平差异有统计学意义(P<0.01)。结论 ICGR15、PA、Child-Pugh评分有助于更好评估肝切除术后患者肝功能代偿情况。
Objective To investigate the effect of the combination of indocyanine green excretion test, serum prealbumin and Child-Pugh score on guiding the hepatectomy. Methods 80 patients with hepatectomy were subject to preoperative Child-Pugh scoring and detection of indocyanine green retention rate at 15 minutes（ICGR15） and serum prealbumin（PA）; the patients were divided into Group A and B according to Child-Pugh score; divided into Group ICG A（ICGR1510%）, Group ICG B（10%ICGR1520%） and Group ICG C（ICGR15≥20%） according to ICGR 15; and divided into Group G（normal liver function）,Group M（mild hepatic dysfunction） and Group S（severe hepatic dysfunction） after the operation. The differences among different groups were compared. Results There were significant differences in the postoperative liver function compensation among the groups with different Child-Pugh scores and among ICGR 15 groups（P〈0.01）. There was statistical difference in the Child-Pugh score, ICGR15 and PA among Group G, M and S（P〈0.01）. Conclusion The ICGR15,PA and Child-Pugh score are conducive to the evaluation of the hepatic function compensation after hepatectomy.
作者
夏联山
仵永泉
张洁
张彩云
邓静
XIA Lian-shan;WU Yong-quan;ZHANG Jie;ZHANG Cai-yun;DENG Jing(The Third Affiliated Hospital of Guangdong Medical University （Longjiang Hospital of Shunde District in Foshan City, Foshan 518318, China)
出处
《广东医科大学学报》
2017年第6期621-624,共4页
Journal of Guangdong Medical University
