联合检测肝硬化患者血清中总胆汁酸、前白蛋白、胆碱酯酶对肝硬化及其分级的临床价值被引量：7

The Clinical Value of Comprehensive Examination on Total Bile Acid, Anterior Albumin and Cholinesterase in Serum of Patients with Cirrhosis and Relevant Classification

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摘要目的探究和分析血清总胆汁酸、前白蛋白、胆碱酯酶的联合检测在肝硬化临床诊治和分级中的应用价值。方法根据Child-Pugh评分,将2014年5月-2017年3月期间的随机选取的60例患者分为A级、B级和C级,3级各20例,并随机选取同时期的60例健康体检者作为对照组,分别对研究组的患者和对照组的健康体检者进行血清总胆汁酸、前白蛋白和胆碱酯酶的检测。结果与对照组的健康体检者相比,肝硬化患者的总胆汁酸显著升高,前白蛋白和胆碱酯酶水平下降;从肝硬化分级情况来看,A级、B级和C级在总胆汁酸、前白蛋白、胆碱酯酶指标水平方面均存在着显著差异。结论对肝硬化患者进行血清总胆汁酸、前白蛋白和胆碱酯酶进行联合检测能够更好的进行肝硬化患者肝功能的评估和判断,有利于肝硬化在临床上的早期诊断、分级和治疗。 Objectives To explore and analyze the application value of serum total bile acid, anterior albumin and cholinesterase in clinical diagnosis and treatment of cirrhosis. Methods According to Child-Pugh score will be in May 2014-March 2017 randomly selected 60 patients were divided into class A and class B and class C, level 3,20 patients and the healthy check-up of the 60 cases were randomly selected from the same period as the control group, respectively, for the healthy check-up of the patients and the control group team for serum total bile acid,anterior albumin and cholinesterase detection. Results Compared with the control group, the total bile acid was significantly increased in patients with cirrhosis, and the level of anterior albumin and cholinesterase decreased. In terms of the classification of cirrhosis, there were significant differences in the levels of grade A, B and C in total bile acids, anterior albumin and cholinesterase indexes. Conclusions Serum total bile acid, anterior albumin and cholinesterase were reactive important indexes of liver reserve function, synthetic function, also was one of the important indexes of liver function damage, for patients with cirrhosis serum total bile acid, anterior albumin and cholinesterase for joint detection could better for the assessment of liver function in patients with cirrhosis and judgment, was helpful for the early diagnosis of liver cirrhosis in clinic, the classification and treatment.

作者史艳春 Shi Yanchun(Shunyi Branch of Beijing Traditional Chinese Medicine Hospital, Beijing 101300, Chin)

机构地区北京中医医院顺义医院

出处《中国病案》 2018年第3期109-112,共4页 Chinese Medical Record

关键词肝硬化总胆汁酸前白蛋白胆碱酯酶 Cirrhosis Total bile acid Anterior albumin Cholinesterase

分类号 R575.2 [医药卫生—消化系统]