摘要
目的结合国内外血栓风险评估模型及指南,分析恶性肿瘤住院患者血栓风险评估及预防干预的效果。方法回顾性分析2016年7月至2017年6月30日我院6个病区收治的恶性肿瘤住院患者详细的临床资料。对符合纳入标准的350个患者的1200份病历逐一查阅、核对并记录所需信息。根据PaduaRAM、CapriniRAM所列的风险因素,制作统一的回顾性表格识别VTE风险因素。最后进行统计、分析、归纳、总结。结果 (1)不同类型肿瘤DVT发生率差异无统计学意义;(2)活动期与否、化疗、PICC置管、升白药物应用、D-二聚体升高与血栓发生,差异无统计学意义;(3)药物干预与血栓发生正相关,差异有统计学意义(P<0.05);(4)将CapriniRAM风险评分低危、中危、高危DVT发生率两两比较,差异有统计学意义(P<0.017);PaduaRAM风险评分低危与高危DVT发生率比较,差异有统计学意义(P<0.05);应用CapriniRAM时,DVT发生率未随评分等级升高而升高,应用PaduaRAM时,DVT发生率随评分等级升高而升高。结论(1)血栓发生与恶性肿瘤发生部位无关;(2)PaduaRAM更适合内科恶性肿瘤住院患者。
Objective To analyze the curative effect of thrombus risk assessment and precaution and intervention on malignant tumor patients according to thrombus risk assessment models and domestic and overseas guides. Methods Detailed clinical data of malignant tumor patients who were admitted to our hospital from July 1st, 2016 to June 30th, 2017 were retrospectively analyzed. 1200 case histories of 350 patients who met the inclusion criteria were consulted one by one, and the information needed was verified and recorded. According to risk factors listed in PaduaRAM and CapriniRAM, unified retrospective table was made to identify VTE risk factors. Finally, data were counted, analyzed, generalized and summarized. Results （ 1 ） DVT occurrence rates in different tumors were not statistically significant. （2） Whether it was in an active period, chemotherapy, PICC, drugs rising white blood cell, D-dimer rising were not statistically significant for the DVT occurrence rates. （ 3 ） Pharmacological intervention had positive cor- relation with the DVT occurrence rates and the difference was statistically significant （P〈0. 05）. （4） High-risk, moderate-risk and low-risk DVT occurrence rates in CapriniRAM were compared in pairs and the differences were statistically significant （ P〈0. 017 ）. Differences between low-risk and high-risk DVT occurrence rates in PaduaRAM were statistically significant （P〈O. 05 ）. The DVT rate rose with growth of score level by using PaduaRAM, but it didn＇t rise with growth of score level by using CapriniRAM. Conclusion （ 1 ） DVT occurrence has nothing to do with occurrence sites of malignant tumor. （2） PaduaRAM is more suitable for malignant tumor inpatients of internal medicine department .
出处
《锦州医科大学学报》
CAS
2018年第1期64-67,共4页
Journal of Jinzhou Medical University
关键词
恶性肿瘤
血栓风险评估模型
预防干预
malignant tumor
thrombus risk assessment model
precaution and intervention
