摘要
目的观察肠复安汤治疗腹泻型肠易激综合征(IBS-D)的临床疗效。方法将48例IBS-D患者按随机数字表法分为治疗组和对照组各24例,对照组用培菲康治疗,治疗组在对照组基础上联用肠复安汤治疗,疗程6周。对比两组临床疗效及治疗前后的近端胃容积、排空分数变化,另选20例健康者作正常组。结果治疗组脱落1例,对照脱落2例,治疗组总有效率91.30%,明显高于对照组之72.73%(P<0.01);治疗组总症状积分改善明显优于对照组(P<0.01);两组近端胃排空分数均高于正常组(P<0.05),治疗后两组排空分数下降,但与治疗前比较无统计学差异(P>0.05)。结论肠复安汤可以显著提高IBS-D治疗的临床疗效,改善患者症状,此外,还能改善患者近端胃功能。
Objective： To observe the clinical effect of Chanjucm Decoction on D-IBS. Methods： 48 cases with IBS were randomly divided into the treatment group and the control group, with 24 cases in each. The control group with-the treatment of Bifico. The treatment group were treated with Changfuan Decoction and Bifieo. The treatment lasted for 6 weeks. The clinical effects and the changes of the proximal gastric volume and emptying score before and after the treatment were compared,and 20 healthy subjects were selected as normal controls. Results： In the treatment group, 1 cases were shedding,2 cases in the control. The total efficative rate was 91.30% in the treatment group,which was significantly higher than that of the control group （72.73%）（P〈 0.01）. The improvement of total symptom score in the treatment group was obviously better than that of the control group （P〈 0.01 ）. The score of proximal gastric emptying in the two groups was higher than that of the normal group （P 〈 0.05）. After treatment,emptying scores of the two groups decreased,but there was no statistical difference com- pared with that before treatment（P〉 0.05）. Conclusion： Changfuan Decoction can significantly improve the clini- cal curative effect on IBS-D, the patient＇s symptoms and the proximal gastric function of IBS.
出处
《中国中医急症》
2018年第2期320-323,共4页
Journal of Emergency in Traditional Chinese Medicine
基金
江苏省中医院院级课题(2015NL-045-01)
关键词
腹泻型肠易激综合征
肠复安
近端胃
胃排空
Diarrhea-predominant irritable bowel syndrome （IBS-D）
Changfuan Decoction
Proximal stomach
Gastric emptying
