摘要
目的:分析中医方药治疗慢性前列腺炎的文献,研究其用药特色和组方规律。方法:检索1977-2016年中国知网数据库,筛选、收集整理治疗慢性前列腺炎有效的文献,摘录中药复方212首建立数据库,以IBM SPSS Modeler软件基于关联规则,通过Apriori算法,分析212首方剂中药和药类、药物归经的使用频次及用药规律。结果:处方中药使用频次排在前5位的依次是丹参(80次,41.9%)、赤芍(78次,40.8%)、王不留行(70次,36.6%)、败酱草(67次,35.1%)、车前子(66次,34.6%);排名前5位的高频药物类型依次为清热药(515次,25.28%)、活血化瘀药(511次,25.09%)、利水渗湿药(357次,17.53%)、补虚药(301次,14.78%)、理气药(130次,6.38%);排名前3位的高频药物归经类型依次为肝经(1275次,23.80%)、胃经(704次,13.14%)、肾经(638次,11.91%)。在关联规则中,符合支持最小置信度(10%)和支持度(75%)的3味药、4味药关联规则分别为13条、4条,清热药、利水渗湿药、活血化瘀药、补虚药是以上规则常见药物组合。结论:治疗慢性前列腺炎以清热利湿、活血化瘀为主,益肾通络为辅。
Objective：To analyze the literature about the treatment of chronic prostatitis with Chinese medicine,and to study administration characteristics and regularity of prescription concerning the literature.Methods： Database of China National Knowledge Infrastructure（CNKI） from 1977 to 2016 was retrieved to select and arrange the effective literature about the treatment of chronic prostatitis.Two hundred and twelve cases of Chinese medicine formula were eventually extracted to establish a database.IBM SPSS Modeler based on association rules was employed to analyze the frequency and regularity of prescription in 212 cases of Chinese medicinal formula,medicine types and meridian tropism of medicine via Apriori algorithm.Results：The top 5 medications applied in the prescriptions in terms of administration frequency were salvia（80 times,41.9%）,red peony root（78 times,40.8%）,the seed of cowherb（70 times,36.6%）,herba Patriniae（67 times,35.1%）,and plantain seed（66 times,34.6%）.The top 5 high frequency medicine types were heat-clearing medicine（515 times,25.28%）,blood-activating and stasis-resolving medicine（511 times,25.09%）,dampness-draining diuretic medicine（357 times,17.53%）,tonifying medicine（301 times,14.78%）,and qi-regulating medicine（130 times,6.38%）.The top 3 high frequency meridian tropism of medicine types were liver meridian（1275 times,23.80%）,stomach meridian（704 times,13.14%） and kidney meridian（638 times,11.91%）.In terms of association rules,the number of association rules in 3 kinds of medicine who accorded with the minimum support confidence（10%） and 4 kinds of medicine who accorded with support degree（75%） was 13 and 4 respectively.Heat-clearing medicine,dampness-draining diuretic medicine,blood-activating and stasis-resolving medicine and tonifying medicine were commonly used in medicine combination based on the above rules.Conclusion：The treatment of chronic prostatitis puts emphasis on clearing heat and removing dampness as well as activating blood and resolving stasis,along with nourishing kidney and activating meridians as the supplemented treatment.
出处
《新中医》
CAS
2018年第1期151-154,共4页
New Chinese Medicine
关键词
慢性前列腺炎
中药疗法
用药规律
数据挖掘
Chronic prostatitis
Chinese medicine therapy
Administration rule
Data mining
