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盐酸青藤碱穴位离子导入治疗膝骨关节炎的临床研究 被引量:7

Clinical Study on Acupoint Iontophoresis with Sinomenine Hydrochloride in Treating Knee Osteoarthritis
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摘要 目的观察盐酸青藤碱穴位离子导入治疗膝骨关节炎的临床疗效。方法将60例膝骨关节炎患者随机分为治疗组和对照组,每组30例。治疗组采用直流电离子导入仪将盐酸青藤碱离子导入特定穴位进行治疗,对照组采用口服美洛昔康片治疗。观察两组治疗前后Lequesne指数评分、VAS评分及膝关节间隙的变化情况。结果两组治疗后Lequesne指数评分及VAS评分与同组治疗前比较,差异均有统计学意义(P<0.01,P<0.05)。治疗组治疗后Lequesne指数评分与对照组比较,差异具有统计学意义(P<0.01)。两组治疗后膝关节间隙组内及组间比较,差异均无统计学意义(P>0.05)。结论盐酸青藤碱穴位离子导入是一种治疗膝骨关节炎的有效方法。 Objective To observe the clinical efficacy of acupoint iontophoresis with Sinomenine hydrochloride in treating knee osteoarthritis (KOA). Method Sixty KOA patients were randomized into a treatment group and a control group, 30 cases each. The treatment group was intervened by iontophoresis with Sinomenine hydrochloride into specific acupoints via a direct current iontophoresis appliance; the control group was intervened by oral administration of Meloxicam tablets. The Lequesne index, Visual Analogue Scale (VAS) and knee joint space were observed before and after the intervention. Result The Lequesne and VAS scores were significantly changed after the treatment in the two groups (P〈0.01, P〈0.05). After the intervention, there was a significant difference in the Lequesne score between the two groups (P〈0.01). After the treatment, the knee joint space didn’t show significant intra-group or between- group differences (P〉0.05). Conclusion Acupoint iontophoresis with Sinomenine hydrochloride is an effecttive method in treating KOA.
出处 《上海针灸杂志》 2018年第1期82-85,共4页 Shanghai Journal of Acupuncture and Moxibustion
关键词 穴位离子导入 骨关节炎 膝关节 穴位疗法 Lequesne指数 VAS评分 膝关节间隙 Acupoint iontophoresis Osteoarthritis, Knee joint Acupoint therapy Lequesne index VAS Knee joint space
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