摘要
背景:目前膝骨关节炎的确切病因及发病机制尚不完全清楚。目的:调查膝骨关节炎患者的临床表现,分析其相关影响因素。方法:收集2007-07/2009-11青岛某医院住院治疗的315例膝骨关节炎患者的一般情况、现病史、既往史、体格检查、X射线片检查、疾病诊断和实验室检查等资料,采用SPSS13.0软件进行χ2检验,分析膝骨关节炎发病的影响因素。结果与结论:①左膝骨关节疼痛占21.6%,右膝疼痛占29.5%,总体上右膝关节疼痛检出率高于左膝(P<0.01)。单膝疼痛占51.1%,双膝疼痛占48.9%,单双膝差异无显著性意义(P>0.05)。②女性临床膝骨关节炎检出率高于男性(P<0.01)。男女检出率均与年龄有关,且随年龄的增加发病率升高。③肥胖人群的膝骨关节炎检出率较非肥胖人群高(P<0.01),不同性别差异无显著性意义。④不同劳动强度人群膝骨关节炎检出率差异具有显著性意义(P<0.01),劳动强度越大检出率越高。⑤绝经女性膝骨关节炎检出率较未绝经女性检出率高(P<0.05),绝经情况分布年龄范围为45～60岁(60岁以上被调查者均已绝经)。提示性别、年龄、体质量指数、职业(工人、家务)、遗传因素等是中老年膝骨关节炎发病的危险因素,其中以年龄因素危险度最高。
BACKGROUND：The precisely etiological factors and pathogenesis of knee osteoarthritis remain unclear.OBJECTIVE：To analyze clinical manifestations of patients with knee osteoarthritis and to explore the influence factors of knee osteoarthritis.METHODS：The general information,such as present illness,past history,physical examination,X-ray film inspection,disease diagnosis and laboratory tests were collected for 315 patients with knee osteoarthritis who were hospitalized in a hospital in Qingdao from July 2007 to November 2009.Statistical comparisons were performed Using SPSS 13.0 software with the χ2 test to analyze influence factors in patients with knee osteoarthritis.RESULTS AND CONCLUSION：①The percentage of left knee joint pain in patients with knee osteoarthritis was 21.6% and in right knee was 29.5%.The percentage of right knee pain was higher than in left knee （P0.01）.The percentage of one knee joint pain in patients with knee osteoarthritis was 51.1% and in double knees was 48.9%.There were no statistically significant differences （P0.01）.②The detection rate of knee osteoarthritis in women was higher than in men （P0.01）.The disease incidence was related to age in an increasing tendency with age.③Compared with non-obesity population,the obesity population suffered a higher incidence of knee osteoarthritis （P0.01）.There were no statistically significant differences in gender.④A higher labor intensity in patient means more incidence of knee osteoarthritis.⑤The detection rate of knee osteoarthritis in postmenopausal women was higher than pre-menopausal women （P0.05）.The postmenopausal ages were 45-60-year （All subjects over 60 years had menopause）.The results demonstrated that gender,age,body mass index,occupation （worker,housework）,as well as genetic results are risk factors that cause knee osteoarthritis in the elderly,especially age,which is the highest risk factor.
出处
《中国组织工程研究与临床康复》
CAS
CSCD
北大核心
2011年第9期1643-1646,共4页
Journal of Clinical Rehabilitative Tissue Engineering Research
