摘要
目的探究妊娠期糖尿病(GDM)的筛查与早期干预对妊娠结局的改善及长期随访对母儿的影响。方法抽取2012年1月—2013年12月濮阳市妇幼保健院门诊建卡作75 g糖耐量实验(OGTT)孕妇1 280例,将其中35孕周前筛查出的98例GDM患者作为研究组,96例35孕周后GDM患者作为对照组。对照组未采取任何干预措施,给予研究组早期干预,2年后对两组患者进行随访。统计对比两组妊娠结局、孕产妇并发症发生率、新生儿情况及随访结果。结果研究组剖宫产率(28.57%)低于对照组(42.71%),自然分娩率(71.43%)高于对照组(57.29%),差异有统计学意义(P<0.05);研究组胎膜早破率(3.06%)、羊水过多率(4.08%)、妊娠期高血压率(4.08%)、酮症酸中毒率(2.04%)均低于对照组(12.50%、12.50%、13.54%、11.46%),差异有统计学意义(P<0.05);研究组高胆红素血症、红细胞增多症、低血糖、呼吸窘迫综合征、巨大儿发生率(5.10%、3.06%、3.06%、4.08%、2.04%)低于对照组(13.54%、15.63%、11.46%、14.58%、10.42%),差异有统计学意义(P<0.05);研究组产妇2型糖尿病发生率(8.16%)、新生儿远期肥胖率(5.10%)及糖尿病发生率(6.12%)低于对照组(19.79%、16.67%、16.67%),差异有统计学意义(P<0.05)。结论早期筛查妊娠期糖尿病并给予患者有效干预措施,可改善妊娠结局,降低孕产妇与新生儿并发症发生率,提高预后效果,具有推广价值。
Objective To explore the effect of early intervention on pregnancy outcome and the improvement of pregnan- cy outcome in patients with gestational diabetes mellitus （ GDM ）. Methods Totally 1280 cases of 75g glucose toler- ance test （OGTY） in pregnant women were selected from January 2012 to December 2013 in our hospital outpatient de- partment, among which 98 cases of GDM patients 35 weeks ago screened as the study group, 96 patients 35 weeks after GDM patients as control group. The control group did not take any intervention, the study group was treated with early intervention, 2 years after the two groups of patients were followed up. We compared the two groups of pregnancy out- comes, maternal complications, neonatal outcomes and follow - up results. Results The cesarean section rate （28. 57% ） in the study group was lower than that in the control group （42. 71% ）, and the natural delivery rate （71.43%） was significantly higher than that in the control group （57. 29% ）, and the difference was statistically signif- icant （ P 〈 0. 05 ） ; The study group of the rate of premature rupture of membranes （ 3.06% ）, polyhydramnios rate （4. 08% ）, pregnancy rate of hypertension （4. 08% ）, ketoacidosis rate （2. 04% ） was lower than the control group （ 12. 50%, 12. 50%, 13.54%, 11.46% ）, the difference was statistically significant （P 〈0. 05） ; The study group of hyperbilirubinemia, polyeythemia, hypoglycemia, respiratory distress syndrome, the incidence of macrosomia （ 5.10% , 3.06%, 3.06%, 4.08%, 2.04%） was lower than that of the control group （13.54%, 15.63%, 11.46%, 14. 58%, 10. 42% ）, the difference was statistically significant （P 〈 0.05 ） ; The incidence of type 2 diabetes mellitus group （8.16%） , neonatal long -term obesity rate （5.10%） and the incidence of diabetes （6. 12% ） was lower than that of the control group （ 19. 79%, 16. 67%, 16. 67% ）, the difference was statistically significant （P 〈0. 05）. Con- clusion Early screening of gestational diabetes mellitus and giving effective intervention measures can improve pregnan-cy outcomes, reduce maternal and neonatal complications, improve the prognosis, with the promotion of value.
作者
王丽娟
WANG Li - juan(Department of Obstetrics and Gynecology, Puyang Maternal and Child Health - Care Hospital, Puyang, Henan 457000, Chin)
出处
《医药论坛杂志》
2017年第5期61-63,共3页
Journal of Medical Forum
关键词
妊娠期糖尿病
筛查
早期干预
妊娠结局
Gestational diabetes mellitus
Screening
Early intervention
Pregnancy outcome
