摘要
目的探讨神经电生理检查对急性炎性脱髓鞘性多发性神经根神经病(AIDP)与急性运动轴索性神经病(AMAN)患者疾病进程及预后的评估效果。方法选取2016年4月—2017年3月在我院就诊的AIDP和AMAN患者68例,均行神经电生理检查,分析其对疾病进程及预后的评估效果。结果 AMAN患者2周时远端复合肌肉动作电位波幅(d CMAP)水平高于4周、12周时,差异有统计学意义(P<0.05);AIDP患者2周时运动传导速度(MCV)、感觉神经动作电位波幅(SNAP)、感觉传导速度(SCV)均高于4周、12周时,差异有统计学意义(P<0.05);AIDP患者2周时运动末梢潜伏期(DML)水平低于4周、12周时,差异有统计学意义(P<0.05);AIDP患者2周时d CMAP水平高于4周时,但略低于12周时,差异有统计学意义(P<0.05);AIDP及AMAN患者心律失常、呼吸肌麻痹、重型患者及预后良好发生率比较,差异无统计学意义(P>0.05);AIDP患者腹泻发生率低于AMAN患者,感觉异常率较高,差异有统计学意义(P<0.05)。结论神经电生理检查可更好的显示AIDP与AMAN患者疾病进程情况,有效评估预后。
Objective To study the effect of nerve electrophysiological examination in evaluation of disease process and prognosis in acute inflammatory demyelinating polyneuropathy（AIDP） and acute motor axonal neuropathy（AMAN） patients.Methods 68 AIDP and AMAN patients from April 2016 to March 2017 were given nerve electrophysiological examination.The evaluation of disease process and prognosis were analyzed.Results The d CMAP level of AMAN patients in 2 weeks was higher than that in 4 weeks,12 weeks（P〈0.05）.MCV,SNAP,SCV of AIDP patients in 2 weeks was higher than that in 4 weeks,12 weeks（P〈0.05）.The DML level of AIDP patients in 2 weeks was lower than that in 4 weeks,12 weeks（P〈0.05）.The d CMAP level of AIDP patients was higher than that in 4 weeks,but was slightly lower than that in 12 weeks（P〈0.05）.There was no difference in the incidence of arrhythmia,respiratory muscle paralysis,serious patients and good prognosis between AIDP and AMAN patients（P〈0.05）.The incidence of diarrhea in AIDP patients was lower than AMAN patients,and the abnormal sensation rate was higher（P〈0.05）.Conclusion Nerve electrophysiological examination can better show disease process of AIDP and AMAN patients and effectively evaluate prognosis.
出处
《中国卫生标准管理》
2017年第26期53-55,共3页
China Health Standard Management
