摘要
为了解草原放牧绵羊胃肠道线虫对目前常用驱虫药物的耐药情况,本研究选取呼伦贝尔草原放牧地区绵羊,采用伊维菌素、丙硫咪唑、氯氰碘柳胺钠分组给药,运用粪便虫卵减少试验进行耐药性田间检测。结果显示,伊维菌素组和丙硫咪唑组给药后30 d内试验所设时间点均无羊只粪便虫卵转阴,且平均EPG仍达800以上;氯氰碘柳胺钠组则在60 h时虫卵即开始全部转阴,30 d时仅有少数羊只检出虫卵。本试验结果进一步证实该地区绵羊胃肠道线虫对伊维菌素和丙硫咪唑产生了较强的耐药性,而对氯氰碘柳胺钠则相对敏感,研究结果为有效地防控家畜寄生虫病提供重要的基础研究资料。
To understand the current situation of resistance of gastrointestinal nematodes in sheep to current anthelmintics（ Iver- mectin, Albendazole, Closantel Sodium）, an investigation was carried out by faecal egg count reduction tests in HulunBuir, Inner Mongolia, China. The results showed that an average EPG of more than 800 was observed in ivermectin group and albendazole group after 30 days, but there were no trans- negative sheep. The trans-negative rate of eggs was 100 in closantel sodium group after 60 hours, and a few eggs were found until 30 days. It is showed that a serious resistance to ivermectin and albendazole was found in this reglens, but sensitive to chlorine sodium.
出处
《中国兽医杂志》
CAS
北大核心
2017年第10期35-37,共3页
Chinese Journal of Veterinary Medicine
基金
公益性行业(农业)科研专项项目(No.201303037)
内蒙古自治区农牧业科学院创新基金项目(2016CXJJMa)
关键词
伊维菌素
丙硫咪唑
氯氰碘柳胺钠
胃肠道线虫
耐药性
Ivermectin
Albendazole
Closantel Sodium
Gastrointestinal Nematodes
Drug resistance
