摘要
目的:分析正电子发射计算机断层显像术/计算机体层摄影术(PET/CT)的18F-氟脱氧葡萄糖(18FFDG)癌灶最大标准摄取值(SUVmax)与子宫内膜癌(EC)临床指标的关系。方法:选择来我院行PET/CT检查的EC患者64例,对其PET、CT与PET/CT所见病灶形态及部位进行显像,分析EC原发灶SUVmax与各临床指标包括肿瘤大小、病理类型及淋巴结转移的相关关系。结果:病理诊断确认原发病灶中32例有淋巴结近处转移,包括20例腹股沟、12例盆腔内转移;腹股沟病灶与盆腔内病灶相比,肿瘤越大SUVmax及平均摄取值(SUVavg)也较大(P<0.05)。病理诊断确认21例有淋巴结远处转移,包括10例肺转移、11例骨转移;淋巴结远处转移病灶类型与肿瘤大小、SUVmax及SUVavg结果呈正相关,肿瘤越大SUVmax越大,同时也显示淋巴结发生转移。EC不同病理类型(腺癌与磷癌)原发灶大小与SUVmax及SUVavg比较,差异无统计学意义(P>0.05)。结论:采用18F-FDG PET/CT诊断EC原发灶,SUVmax越大肿瘤也越大,淋巴结发生转移越显著,但其与病理类型无明显关系。
Objective： To analyze the relationship between the maximum intake of PETCT 18F-FDG and the clinical indicators of endometrial carcinoma. Methods： Sixty-four cases of endometrial cancer （EC） undergoing PET/CT in our hospital were selected as research subjects. PET, CT and PET/CT findings of lesion morphology and location were used to analyze relationship between the endometrial carcinoma maximum standard uptake value （SUVmax） and the clinical indicators, including tumor size, lymph node metastasis and pathological types. Results ： The pathological diagnosis confirmed that there were 32 cases of lymph node metastasis in primary lesion, 20 cases of inguinal lesion and 12 cases of pelvic lesions. Comparison between the inguinal lesions and the pelvic lesions showed that the bigger the tumor was, the greater the SUVmax and $UVavg （ P 〈 0.05 ）. The pathological diagnosis confirmed 21 cases of distant lymph node metastasis, 10 cases of lung metastasis and 11 cases of bone metastasis. The results showed that the bigger the tumor related to the metastatic lesions. The distant metastasis was, the greater the SUVmax, and that was also closely of lymph node type was positively correlated with tumor size, SUVmax and SUVavg results. Comparison of primary lesion size of different pathological types of EC with SUVmax and SUVavg showed no statistical difference （ P 〉 0.05 ）. Conclusion： The primary tumor of endometrial carcinoma can be diagnosed by PET/CT 18F-FDG, which shows that the greater the value of SUVmax is, the bigger the tumor and that the more obvious the lymph node metastasis occurs.
出处
《现代医学》
2017年第10期1453-1457,共5页
Modern Medical Journal
基金
梅州市医药卫生科研项目(2017-B-59)
