摘要
目的对卵巢储备功能不同患者的抗苗勒管激素(AMH)水平进行分析比较,探讨其与窦卵泡计数(AFC)、促卵泡激素(FSH)、雌二醇(E2)、黄体生成素(LH)及睾酮(T)的相关性。方法选取2016年1-2月在该院接受治疗的168例患者,根据其卵巢储备功能的差异分为4组(A、B、C、D组)。A组患者46例,为多囊卵巢综合征患者;B组患者44例,为卵巢功能减退患者;C组患者43例,为卵巢早衰患者;D组患者35例,为卵巢储备功能正常患者。分析比较4组患者的血清AMH、AFC及基础内分泌激素水平,对其相关性进行分析。结果在AFC及基础内分泌激素等常规指标方面,4组间比较差异有统计学意义(P<0.05);在血清AMH水平方面,A组最高,C组最低,4组间比较差异有统计学意义(P<0.05);Pearson相关分析显示,AMH水平与AFC、E2、T间呈明显正相关,AMH与FSH、LH间呈明显负相关。结论血清AMH水平结合AFC、基础内分泌激素水平可用于卵巢储备功能的预测、评估,具有重要临床意义。
Objective To analysis and compare the levels of AMH in patients with different ovarian reserve function,and investigate the correlation with AFC,FSH,E2,LH,and T.Methods 168 cases of patients with different ovarian reserve function were selected,which were treated in hospital from January to December 2016,and were divided into A,B,C,D group according to the different ovarian reserve function.46 patients of A group with polycystic ovary syndrome,44 patients of B group with ovarian dysfunction,43 patients of C group with premature ovarian failure,35 patients of D group with normal ovarian reserve.The levels of serum AMH,AFC and basic endocrine hormone between 4 groups were analyzed and compared.Results In the terms of AFC and basic endocrine hormone,the difference between the 4 groups were statistically significant（P〈0.05）;In the terms of serum AMH,the highest was A group and the lowest was C group,the difference between the 4 groups were statistically significant（P〈0.05）,and Pearson correlation analysis showed that there was a significant positive correlation between AMH with AFC,E2,T;there was a significant negative correlation between AMH with FSH,LH.Conclusion Serum AMH combined with AFC,basic endocrine hormone for the prediction and evaluation of ovarian reserve function,has important clinical significance.
出处
《检验医学与临床》
CAS
2017年第21期3173-3174,3177,共3页
Laboratory Medicine and Clinic
关键词
卵巢储备功能
抗菌勒管激素
窦卵泡计数
内分泌激素
ovarian reserve function
anti-mullcrian hormone
antral follicle count
endocrine hormone
