摘要
目的探讨齐拉西酮联合心理干预在青少年精神分裂症中的临床疗效。方法选取2014年1月~2016年12月医院收治青少年精神分裂症患者90例,随机分为对照组(n=45)和观察组(n=45)。对照组采用齐拉西酮治疗,观察组在对照组的基础上联合心理干预治疗,采用阳性和阴性症状量表(PANSS)对两组治疗效果进行评估。结果观察组治疗后有效率为94.1%,对照组为67.6%,两组差异有统计学意义(P<0.05);治疗后,观察组治疗后阳性量表、阴性量表、一般病理及量表总分均低于对照组(P<0.05)。结论青少年精神分裂症患者在齐拉西酮基础上联合心理干预治疗效果理想,值得推广应用。
Objective To investigate the effect of ziprasidone combined with psychological intervention in the treatment of adolescent with schizophrenia. Methods 90 teenager patients with schizophrenia were collected and then randomly divided into the control group（n=45）and the observation group（n=45）in our hospital from January 2014 to December 2016. The control group was treated with ziprasidone,while the observation group was treated with psychological intervention combined with ziprasidone,The Positive and Negative Syndrome Scale（PANSS） was used to evaluate the therapeutic effects of the 2 groups. Results The total effective rate of the observation group after treatment was 94.1%,which was high than that of the control group 67.6%（P〈0.05）;The PANSS score showed no significant difference between the two groups before treatment（P〈0.05）The positive scale scores,negative scale scores,general pathological scale scores and total scors of the observation group were all lower than those of the control group after treatment（P〈0.05）. Conclusion The effect of psychological intervention combined with ziprasidone in the treatment of adolescents with schizophrenia is significantly effective,thus,it is worthy of popularization and application.
作者
杨玲
谭成万
付艳梅
曹宏波
张莉琳
YANG Ling TAN Chengwan FU Yanmei et al(Mental Health Center in Enshi of Hubei Province, Enshi 445000, Chin)
出处
《国际精神病学杂志》
2017年第5期794-796,共3页
Journal Of International Psychiatry
关键词
齐拉西酮
心理干预
青少年
精神分裂症
Ziprasidone
Psychological intervention
Adolescent
Schizophrenia
