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肥胖高血压患者脉搏波传导速度与内脏脂肪素的相关性研究

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摘要 目的探讨肥胖高血压患者脉搏波传导速度(PWV)与血清内脏脂肪素(Visfatin)水平的相关性。方法将原发性高血患者140例,依据体重指数(BMI)≥28 kg/m2分为肥胖高血压组70例、单纯高血压组70例,将70例同期健康体检者作为对照组。分别测定肱踝脉搏波传导速度(ba PWV)和血清Visfatin。结果高血压组ba PWV和血清Visfatin水平均高于对照组(P<0.05),肥胖高血压组ba PWV和血清Visfatin水平高于单纯高血压组(P<0.05)。两变量直线相关分析显示,肥胖高血压组BMI、SBP、HOMA-IR与ba PWV呈正相关性(P<0.05)。Visfatin水平与BMI、WC、SBP、ba PWV呈正相关性(P<0.05)。Logistic回归进行相关性分析结果显示,BMI、SBP、HOMA-IR、Visfatin是ba PWV的主要影响因素。结论 Visfatin和肥胖高血压患者的脉搏波传导速度增加密切相关。
出处 《宁夏医学杂志》 CAS 2017年第10期910-912,共3页 Ningxia Medical Journal
基金 宁夏卫计委重点科研计划资助项目(2012100)
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