摘要
目的:研究与分析血培养阳性报警时间对临床病原菌鉴别的意义。方法:选取2016年2月-2017年2月本院发热患者送检病原微生物室的血培养标本为研究对象,分析其血培养阳性报警时间对鉴别临床病原菌的应用。结果:7226份血培养标本检测阳性率为5.83%(421/7226),在421份血培养阳性瓶中,同时为阳性标本的厌氧瓶与需氧瓶共377份(89.55%),仅报阳性的厌氧瓶为21份(4.99%),仅报阳性的需氧瓶为23份(5.46%)。421份报阳性瓶中,共检出菌株205株,病原菌主要以大肠埃希菌、铜绿假单胞菌、肺炎克雷伯菌、金黄色葡萄球菌及阴沟肠杆菌为主;阳性报警时间平均为(24.53±2.47)h。而需氧瓶与厌氧瓶的平均阳性报警时间分别为(18.60±1.29)、(17.30±1.31)h,两者比较差异无统计学意义(P>0.05),各病原菌以及污染菌的平均阳性报警时间比较,差异有统计学意义(P<0.05)。结论:血培养阳性报警时间有助于初步鉴别临床病原菌及污染菌,为临床明确诊断提早使用抗生素提供实验室依据。
Objective：To study and analyze the significance of time to positivity of blood culture for clinical pathogenic bacteria identification.Method：The blood culture specimens of pathogenic microorganisms from fever patients in our hospital from February 2016 to February 2017 were selected as the research objects,the time to positivity of blood culture and its application in clinical pathogenic bacteria identification were analyzed.Result： The positive rate of 7226 blood culture specimens was 5.83%（421/7226）,there were 377 bottles（89.55%） of anaerobic and aerobic bottles positive samples in 421 blood culture positive bottles,only 21（4.99%） of positive anaerobic bottles were reported,only 23（5.46%） of positive aerobic bottles were reported.205 strains were detected in 421 positive bottles.The main pathogenic bacteria were escherichia coli,pseudomonas aeruginosa,klebsiella pneumoniae,staphylococcus aureus and enterobacter cloacae,the average time to positivity was（24.53±2.47）h.the average time to positivity of aerobic bottles and anaerobic bottles was（18.60±1.29） and（17.30±1.31）h respectively,the difference was not statistically significant（P〉0.05）.The average time to positivity of pathogenic bacteria and contaminated bacteria were compared,the difference was statistically significant（P〈0.05）.Conclusion： The blood culture time to positivity is helpful for the clinical pathogenic bacteria identification.It would provided evidence of laboratory for the diagnosis and early use of antibiotics for patients.
出处
《中国医学创新》
CAS
2017年第30期121-124,共4页
Medical Innovation of China
关键词
血培养
阳性报警时间
病原菌鉴别
临床意义
Blood culture
Time to positivity
Pathogenic bacteria identification
Clinical significance
