摘要
生物医用可降解镁合金具有良好的机械性能、生物可降解性且降解产物可随人体新陈代谢排出体外,被誉为"下一代生物医用金属材料"。然而,过快的降解速率制约着镁合金在临床上的应用。从生物降解性和生物相容性的角度,综述医用可降解镁合金表面改性研究进展。重点介绍医用可降解镁合金表面微弧氧化涂层、Ca–P基涂层和惰性陶瓷涂层等生物陶瓷涂层的制备及其优缺点。最后,基于医用镁合金的临床应用要求和现有表面改性技术特点,展望医用可降解镁合金表面改性的未来发展方向。
Biodegradable magnesium alloy as the next generation of biomedical metal becomes popular in the field of biomaterials due to the suitable mechanical properties and its degradation products can be discharged via metabolism.However,the fast degradation of magnesium and its alloys restricts its clinic application.From the viewpoint of biodegradation and biocompatibility,recent progress in surface modification of biodegradable magnesium alloys for biomedical application was reviewed.Recent studies on the preparation of bioceramic coating(i.e.,plasma electrolytic oxidation(PEO)coating,Ca-P based coating and bioinert ceramic coatings on magnesium alloys)were given.In addition,future development on the surface modification of magnesium alloys was also proposed based on the requirement of clinical application and the modification technologies.
作者
刘宣勇
彭峰
LIU Xuanyong;PENG Feng(State Key Laboratory of High Performance Ceramics and Superfine Microstructure,Shanghai Institute of Ceramics,ChineseAcademy of Sciences,Shanghai200050,China)
出处
《硅酸盐学报》
EI
CAS
CSCD
北大核心
2017年第10期1421-1431,共11页
Journal of The Chinese Ceramic Society
基金
国家杰出青年科学基金(51525207)项目
关键词
镁合金
陶瓷涂层
生物相容性
生物降解性
magnesium alloys
ceramic coating
biocompatibility
biodegradable
