摘要
复方乳酸钠注射液主要成分为氯化钠、氯化钾、氯化钙及乳酸钠等。目前,在该制剂的分析中,常以银量法和离子交换-洗脱-滴定法或碳化-酸碱剩余滴定法分别测定总氯量及乳酸钠含量。本文采用离子色谱法在30
Ion chromatographic separation and determination of total chloride and sodium lactate contained in compound sodium lactate injection were studied. Waters ILC-1 Ion/Liquid Chromatograph, 50×4.6 mm i. d. stainless steel IC-PAK A column, the solution of 1 mmol/L phthalic acid (pH 4.0) as mobile phase at a flow rate of 0.8 ml/min, and model 430 conductivity detector with 2. 5 μSFS were used. Good results could be obtained by using external standard single-point calibration method. The average recoveries of chloride and sodium lactate were 98.46% and 101.1%, and the correlation coefficients were 0.9995 (n=12) and 0.9956 (n=12) respectively.
出处
《中国药科大学学报》
CAS
CSCD
北大核心
1991年第1期27-29,共3页
Journal of China Pharmaceutical University
关键词
乳酸钠注射液
氯化物
乳酸盐
Compound sodium lactate injection
Chloride
Lactate
Ion chromatography
