摘要
目的:研究老年烧伤患者凝血功能变化的临床意义。方法:收集2014年1月至2016年12月首次就诊于泰山医学院附属成武医院烧伤科182例老年烧伤患者作为观察组,男性104例,女性78例。以同期入院的80例中青年烧伤患者作为对照组,男性48例,女性32例。收集两组患者凝血功能检测结果并比较。结果:观察组比对照组凝血活酶时间(APTT)缩短,凝血每原时间(PT)、纤维蛋白原(Fib)、血不板计数(PLT)、D-二聚体(D-D)测定值升高(P<0.05)。纤维蛋白原(Fib)、D-二聚体水平的变化与老年烧伤深度及严重程度有关,中、重度烧伤患者与轻度烧伤患者相比D-D、Fib明显升高(P<0.05),老年Ⅲ度烧烫伤患者与Ⅰ、Ⅱ度烧烫伤患者相比D-二聚体升高,APTT缩短(P<0.05)。结论:老年烧伤患者伴随其凝血纤溶系统的异常激活可导致大面积烧伤患者以及中重度烧伤患者更易出现血液的高凝状态,在临床上监测烧伤患者凝血功能可作为预防其发生血栓的有效措施。
Objective：To study the changes of coagulation function in elderly burn patients and to explorere the clinical significance of the changes. Methods：We retrospectively analyzed the clinical data of 182 patients as a trial group with elderly burn in the affiliated hospital of Taishan medical college chengwu from January 2014 to December 2016 and collected blood coagulation test results. There were 104 males and 78 females. 80 cases of middle - aged patients admitted to the same period as the control group,There were 48 males and 32 females. The results of coagulation test were collected and compared. Results： Compared with the control group,coagulation parameters including APTY, PT,TF, Fib, PLT, D-Dimer werestatistically higher in the trial group （P〈0.05）. The levels of fibrinogen （Fib） and D- D were related to the depth and severity of burn in elderly patients. D-D and Fib were significantly higher in patients with moderate or severe burn and mild burn （P〈0.05）. The old Ⅲ degree burn patients with Ⅰ , Ⅱ degree burn patients compared to D-D significantly increased （P〈0.05）. Conclusion： Most of the patients with large area burn and severe burn patients have abnormal changes of coagulation and fibrinolysis system. So monitoring the coagulation parameters of burn patients can be used as an effective measure to prevent blood clot.
作者
高尚法
袁继宝
朱自江
张帆
周中民
孟凡青
于杨
侯光谱
Gao Shanfa Yuan Jibao Zhu Zijiang Zhang Fan Zhou Zhongmin Meng Fanqin Yu Yan Hou Guangpu(The Affiliated Chengwu Hospital of Taishan Medical College, Chengwu 274200,China Gansu Provincial Hospital,Lanzhou 730000,China Gansu University of Chinese Medicine,Lanzhou 73000,China)
出处
《甘肃医药》
2017年第9期714-717,共4页
Gansu Medical Journal
关键词
老年烧伤
凝血功能
检测
临床意义
elderly burn
blood coagulation
detection
clinical significance
