摘要
目的探讨血必净联合抗生素治疗重度烧伤的临床效果。方法选取2014年6月~2016年6月我院收治的74例重度烧伤患者为研究对象,随机均分观察组与对照组,每组37例。对照组采取综合治疗法,观察组在此基础上采取血必净、抗生素联合治疗。观察两组生命体征变化与治疗有效率。结果观察组的有效率(83.78%)高于对照组(59.46%),差异有统计学意义(P<0.05);两组治疗后白细胞(WBC)计数、谷丙转氨酶(ALT)、谷草转氨酶(AST)、肌酐(Cr)、血尿素氮(BUN)水平均显著下降(P<0.01),血浆凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)均明显缩短(P<0.05),观察组治疗后WBC计数、ALT、AST、Cr、BUN水平显著低于对照组,PT、APTT明显短于对照组,差异有统计学意义(P<0.01)。结论抗生素合用血必净对重度烧伤患者治疗效果显著,值得应用。
Objective To explore the clinical effect of Xuebijing combined with antibiotics in the treatment of severe burn.Methods From June 2014 to June 2016,74 patients with severe burn treaded in our hospital were selected as research objects.They were evenly divided into observation group and control group in random,with 37 cases in each group.In the control group,comprehensive therapy was used,while in the observation group,on the basis of the control group,Xuebijing combined with antibiotic was used.The changes of vital signs and therapeutic effective rate were observed.Results The effective rate in the observation group was 83.78%,significantly higher than that in the control group accounting for 59.46% with a statistical difference(P〈0.05).After therapy,the white blood cell count,alanine aminotransferase(ALT),aspartate aminotransferase(AST),creatinine(Cr) and blood urea nitrogen(BUN) were all greatly decreased in both groups(P〈0.01).Prothrombin time(PT) and activated partial thromboplastin time(APTT) were both obviously shortened(P〈0.05).The changes of these indicators in the observation groups were all superior to those in the control group,which were displayed statistical differences between the two groups(P〈0.01).Conclusion Antibiotics combined with Xuebijing has a remarkable effect on treating severe burn,which is worthy of application.
出处
《中国当代医药》
2017年第26期129-131,共3页
China Modern Medicine
关键词
血必净
抗生素
重度烧伤
Xuebijing
Antibiotics
Severe burn