摘要
目的了解烧伤患者感染病原菌分布及耐药性。方法回顾性分析医院2011年1月-2016年12月6年烧伤病区送检的标本4742份,分析阳性标本来源,病原菌分布及药敏结果。结果 4742份标本中阳性标本为1960份,阳性率为41.33%,共检出2197株病原菌,主要来源为烧伤创面分泌物占72.19%;阳性标本中分离出革兰阴性菌占57.85%,革兰阳性菌占41.15%,真菌及其他占1.00%;金黄色葡萄球菌分离率最高,占分离病原菌的26.54%,而耐甲氧西林(MRSA)占金黄色葡萄球菌的74.27%;药敏试验显示,目前各检出菌的耐药性上升趋势严重。结论烧伤细菌感染以革兰阴性菌为主,对碳青霉烯类耐药率有上升的趋势,在检出率方面MRSA也有增高的趋势,临床应重视根据药敏试验用药,以延缓细菌耐药率。
OBJECTIVE To understand the distribution and drug resistance of pathogenic bacteria of wound infections in burned patients.METHODS A total of 4742 cases of specimens from burn wards in the hospital from Jan.2011 to Dec.2016 were retrospectively analyzed.The sources of positive specimens,distribution and drug sensitive results of pathogenic bacteria were analyzed.RESULTS Among 4742 specimens,the positive specimens were 1960cases（41.33% ）and 2197 strains of pathogenic bacteria were detected.The main source of burn wound secretions accounted for 72.19% .There were 57.85% of gram-negative bacteria,41.15% of gram-positive bacteria,and1.00% of fungi and others,respectively.The highest isolation rate was Staphylococcus aureus,accounting for26.54% of the isolates,whereas methicillin-resistant S.aureus（MRSA）accounted for 74.27% of S.aureus.Meanwhile,drug sensitivity tests showed that the resistance of each detected bacteria increased.CONCLUSION Gram-negative bacteria are the main pathogens of bacterial infection in burn wound infections,and there is a rising trend of carbapenem resistance rate.In the detection rate,MRSA also has an increasing tendency.Therefore,clinical attention should be paid according to drug sensitivity test in order to delay the rate of bacterial resistance.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2017年第18期4198-4201,共4页
Chinese Journal of Nosocomiology
基金
甘肃省卫生行业科研基金资助项目(GSWSKY2017-49)
关键词
烧伤患者
创面感染
病原菌
耐药性
Burned patient
Wound infection
Pathogenic bacteria
Drug resistance
