摘要
目的探讨患者卒中后抑郁(PSD)的影响因素及其对生活质量的影响。方法随机选取2015年2月至5月中国医科大学附属第一医院住院的52例脑卒中且入院时经抑郁量表评估未出现抑郁的患者作为研究对象,对其进行为期6个月的随访,统计其年龄、既往疾病史、患病类型、患病原因、治疗方法等情况,通过汉密尔顿抑郁量表(HAMD)、抑郁自评量表(SDS)评估患者抑郁情况;卒中专用生活质量评分(SS-QOL)、改良Rankin量表(MRS)评估其生活质量,分层抽样方法得出原始数据,使用SPSS 17.0对结果进行统计学分析。结果与中青年患者(<60岁)比较,老年患者(≥60岁)PSD的患病率更高(P<0.05);在脑梗死患者中,心源性栓塞引起的脑梗死较其他病因PSD的可能性更大(P<0.05),不同发病部位的脑梗死患者在PSD方面也有差异,基底节区梗死的患者PSD的可能性较其他区域大(P<0.01);高血压、糖尿病、冠心病等既往疾病对PSD无显著影响;脑卒中类型为脑出血还是脑梗死以及是否接受过溶栓治疗对患者患PSD的发病亦无显著影响;PSD会对患者生活质量产生不利影响。结论基底节区患病的老年(≥60岁)脑梗死患者、心源性栓塞引起的脑梗死患者是PSD的易发人群,应对其高度重视。PSD会对患者的生活质量产生不利的影响。
Objective To explore the influencing factors of patients with post-stroke depression （PSD） and study their impact on the quality of life. Methods Fifty-two stroke patients admitted to the First ospital of China Medical University from February 2015 to May 2015 were randomly selected for the study, and these patients did not suffer depression as evaluated by the depression rating scale. Their age, history of diseases, types of diseases, cause of illness, disease area and treatments were collected in detail. These patients were followed up for six month. The mental state was assessed by Hamilton depressive scale （HAMD） and self-rating depressive scale （SDS） . The life quality was evaluated by stroke specific quality of life score （SS-QOL） and modified Rankin scale （mRS）. These data were selected by stratified sampling method and analyzed by SPSS 17.0 software. Results The incidence of PSD in elder patients （ ≥60 years） was significantly higher than in the younger patients （P 〈 0.05 ）. Patients with cardiogenic cerebral embolism are more likely to suffer from PSD （P 〈 0.05 ）. The patients with infarction in different regions have different probability to suffer from PSD. Those patients with cerebral infarction in basal ganglia exhibited more possibility on PSD than others （P 〈 0.01 ）. Previous disease, including hypertension, diabetes and coronary disease, had no effects on PSD. There were no significant effects of stroke types and thrombolytic therapy on PSD. PSD had an unfavorable effect on the life quality of the patients. Conclusion The patients with cerebral infarction in basal ganglia, aged over sixty and cardiogenie cerebral embolism are prone to PSD, and we should pay more attention to them. PSD has a negative impact on the quality of life of patients.
出处
《中国医科大学学报》
CAS
CSCD
北大核心
2017年第9期844-847,共4页
Journal of China Medical University
关键词
卒中后抑郁
年龄
既往疾病史
生活质量
post-stroke depression
age
previous medical history
quality of life
