摘要
目的探讨氟哌噻吨美利曲辛治疗脑卒中后抑郁(post stroke depression disorder,PSD)的疗效。方法选取我院PSD患者72例随机分为对照组和治疗组,每组36例。对照组予以常规抗血小板聚集、调脂稳定斑块、控制血压、控制血糖等综合治疗,治疗组在以上综合治疗基础上予以口服氟哌噻吨美利曲辛治疗;于治疗前、治疗4周、治疗12周时分别对2组患者行汉密尔顿抑郁量表(HAMD)评定、NIHSS评分及BI指数测定。结果治疗组治疗前、4周、12周时HAMD评分、NIHSS评分、BI指数较前均有明显改善,差异具有统计学意义(P<0.05),与对照组比较,差异具有统计学意义(P<0.05)。结论氟哌噻吨美利曲辛治疗PSD疗效显著,且能改善脑卒中患者预后,提高卒中患者生活质量。
Objective To observe the effects of flupentixol and melitrance tablets on post-stroke depression （PSD）. Meth- ods A total of 72 patients with PSD were randomly divided into treatment group（n=36）and control group（n=36）. The pa- tients in the controlgroup received comprehensive therapy of antiplatelet, regulating blood lipids, stablizing plaque, controlling blood pressure and glucose and so on. While the patients in the treatment group received an additional flupentixol and meli- trance tablets treatment. All patients were assessed with Hamilton Depression Scale （HAMD）, NIHSS, BI before and at 4 weeks, 12weeks after treatment. Results HAMD score ,NIHSS,BI in the treament group improved remarkably after both 4- week and 12-week treatment（P〈0.05）, and had significant difference with the control group（P〈0.05）. Conclusion Flu- pentixol and melitrance tablets remarkably improves the conditions of patients with PSD, and it can improve prognosis of pa- tients with stroke.
出处
《中国实用神经疾病杂志》
2014年第1期41-42,共2页
Chinese Journal of Practical Nervous Diseases
关键词
氟哌噻吨美利曲辛片
卒中后抑郁
疗效分析
Flupentixol and melitrance tablets
Post-stroke depression disorder
Treatment outcome
