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胎膜早破与急性绒毛膜羊膜炎的关系及绒毛膜羊膜炎致病菌群研究 被引量:21

Relationship between premature rupture of membranes and acute chorioamnionitis and pathogenic flora of chorioamnionitis
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摘要 目的探讨胎膜早破与急性绒毛膜羊膜炎的关系及绒毛膜羊膜炎病原菌分布情况,为临床治疗提供参考依据。方法选择医院2014年-2015年足月胎膜早破孕妇98例和未足月胎膜早破孕妇98例作为胎膜早破组,未胎膜早破足月产孕妇98例和早产孕妇98例作为未胎膜早破组,收集孕妇的临床资料、急性绒毛膜羊膜炎发生情况及细菌培养结果。结果足月胎膜早破患者急性绒毛膜羊膜炎的发生率低于未足月胎膜早破患者;胎膜早破组患者急性绒毛膜羊膜炎的发生率高于未胎膜早破组;足月胎膜早破急性绒毛膜羊膜炎患者的发生率高于足月产患者;未足月胎膜早破急性绒毛膜羊膜炎患者的发生率高于早产患者,差异均有统计学意义(P<0.05);共培养出病原菌24株,以大肠埃希菌为主,共13株占54.2%。结论胎膜早破孕妇急性绒毛膜羊膜炎的发生率升高,未足月胎膜早破孕妇的急性绒毛膜羊膜炎的发生率高于足月胎膜早破孕妇,急性绒毛膜羊膜炎的主要病原菌为大肠埃希菌。 OBJECTIVE To explore the relationship between premature rupture of membranes and acute chorioamnionitis and the distribution of chorioamnionitis pathogens,so as to provide references for clinical treatment.METHODS A total of 98 patients with full-term premature rupture of membranes and 98 patients with preterm premature rupture of membranes were selected as the premature rupture of membranes group,and 98 cases of full-term pregnant women and 98 cases of premature pregnant women without premature rupture of membranes were selected as no premature rupture of membranes group.The clinical data of pregnant women,the incidence of acute chorioamnionitis and bacterial culture results were collected.RESULTS The incidence of acute chorioamnionitis in patients with full-term rupture of membranes was lower than that in patients with preterm premature rupture of membranes(P〈0.05).The incidence of acute chorioamnionitis in patients with premature rupture of membranes was significantly higher than that in patients without premature rupture of membranes(P〈0.05).The incidence of acute chorioamnionitis in the patients with full-term rupture of membranes was significantly higher than that in the full-term group(P〈0.05).The incidence of acute chorioamnionitis in the preterm premature rupture of membranes was significantly higher than that in the preterm labor group(P〈0.05).Totally 24 cases of pathogens were cultured,which were mainly 13 strains of Escherichia coli,accounting for 54.2%.CONCLUSIONThe incidence of acute chorioamnionitis in pregnant women with premature rupture of membranes is high.The incidence of acute chorioamnionitis of preterm premature rupture of membranes in pregnant women is higher than full-term premature rupture of membranes in pregnant women.The main pathogenic bacteria of acute chorioamnionitis are E.coli.
出处 《中华医院感染学杂志》 CAS CSCD 北大核心 2017年第14期3281-3284,共4页 Chinese Journal of Nosocomiology
基金 浙江省医药卫生基金资助项目(2014KYB254)
关键词 胎膜早破 急性绒毛膜羊膜炎 病原菌 Premature rupture of membranes Acute chorioamnionitis Pathogens
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