摘要
目的探究达英-35联合二甲双胍治疗多囊卵巢综合征后促排卵效果,总结临床经验。方法针对40例多囊卵巢综合征患者使用达英-35治疗,并归为对照组,针对另外40例患者使用达英-35联合二甲双胍治疗,并归为观察组;此后观察2组患者相关激素水平和促排卵情况,入选患者均为镇海区人民医院2016年1月~2016年12月间收治。结果 2组患者的T、FSH、LH、E2等激素水平在治疗前均无明显差异,经过分组治疗后均出现一定改善,但是观察组患者改善明显更加显著;比较2组卵巢过度刺激综合征和周期取消发生率可见明显差异;观察组的妊娠率为47.5%,对照组妊娠率为15.0%,组间比较差异有统计学意义（P〈0.05）。结论达英-35联合二甲双胍治疗多囊卵巢综合征后促排卵效果观察发现,其相比单纯的达英-35治疗而言,能够提高患者各项激素水平,同时帮助其改善临床情况,最终使得排卵情况得到改善,提高妊娠率,因此值得临床借鉴。
Objective To investigate the effect of Daying-35 combined with metformin on ovulation induction after polycystic ovary syndrome,and to summarize the clinical experience. Methods Forty patients with polycystic ovary syndrome were treated with Daying-35 and treated as control group. Forty-five patients were treated with meta-35 combined with metformin and treated as observation group. After treatment,Level and ovulation induction,selected patients were our hospital in January 2016 to December 2016 between the treatment. Results There were no significant differences in T,FSH,LH,E2 and other hormone levels between the two groups before treatment. After treatment,the improvement of the treatment group was significantly more obvious; compared with the two groups of ovarian hyperstimulation syndrome and The rate of pregnancy was 47. 5% in the observation group and 15. 0% in the control group. The difference between the two groups was significant（ P 〈0. 05）. Conclusion The effect of Daying-35 combined with metformin on ovulation induction after polycystic ovary syndrome was found to improve the progesterone level and improve the clinical status of the patients. Making the ovulation situation improved,improve the pregnancy rate,it is worth clinical reference.
出处
《中国生化药物杂志》
CAS
2017年第7期63-65,共3页
Chinese Journal of Biochemical Pharmaceutics
