摘要
自噬是细胞固有的一种物质降解再利用过程,不仅在维持细胞内环境稳定方面发挥重要作用,也在肿瘤治疗领域有着广泛的影响。肺癌是最常见的一种恶性肿瘤,放射治疗作为肺癌的重要治疗手段之一,可以显著改善患者预后。越来越多的证据表明自噬对肺癌放射治疗效果具有重要影响。本文就自噬在肺癌放射治疗中的作用作一综述。
Autophagy is an inherent process of substance degradation and recycling in cells. It not only plays an important role in maintaining internal environment invariably,but also has a wide influence in the field of tumor treatment. Lung cancer is one of the most common malignant tumors,as one of the important treatment of lung cancer,radiotherapy can significantly improve the prognosis of patients. An increasing number of evidences suggest that autophagy has an important effect on lung cancer radiotherapy results. In this paper,we review the role of autophagy in lung cancer radiotherapy.
出处
《现代肿瘤医学》
CAS
2017年第15期2514-2517,共4页
Journal of Modern Oncology
基金
吴阶平医学基金会资助项目(编号:2015
320.6799.15035)
江苏省卫生厅科技资助项目(编号:2014H201426)
徐州市科技局资助项目(编号:2015KC15SH002)
关键词
肺癌
自噬
放射治疗
lung cancer
autophagy
radiotherapy