摘要
Objective： To observe different efficacies of low-frequency electroacupuncture（EA） on pancreatic endocrine system in male and female patients with simple obesity due to spleen deficiency-related dampness. Methods： A total of 80 simple obesity patients were assigned to a male group（n=37） and a female group（n=43）. Both groups received a 30-minute low-frequency EA at Yinlingquan（SP 9）, Sanyinjiao（SP 6）, Zusanli（ST 36）, Fenglong（ST 40）, Quchi（LI 11）, Tianshu（ST 25）, Zhongwan（CV 12）, Shuifen（CV 9）, Qihai（CV 6） and Guanyuan（CV 4）. The treatment was done once a day, and 10 times made up a course of treatment. Patients in both groups were treated for 2 courses. Then the changes in body mass index（BMI）, serum insulin, insulin antibodies and leptin level in the two groups were observed and analyzed. Results： After treatment, the BMI, serum insulin, insulin antibodies and leptin levels were significantly reduced in both groups（P〈0.01 or P〈0.05）; the BMI and serum insulin concentration were more significantly reduced in the male group than those in the female group（both P〈0.01）; and the leptin level was more significantly reduced in the female group than that in the male group（P〈0.01）. Conclusion： EA can significantly regulate BMI and pancreatic endocrine system in both men and women with simple obesity; however, there is a gender difference： better effect for men in reducing BMI and serum insulin and better effect for women in reducing serum leptin level.
目的:探讨低频电针对男、女脾虚湿盛型单纯性肥胖症患者胰岛内分泌系统调节作用的差异性。方法:共纳入单纯性肥胖症患者80例,男性组37例,女性组43例,采用低频电针刺激两组患者的阴陵泉、三阴交、足三里、丰隆、曲池、天枢、中脘、水分、气海和关元,留针30 min,每天治疗1次,10次为1疗程,治疗2个疗程。观察两组患者治疗前后身体质量指数(BMI)及血清胰岛素、胰岛素抗体及瘦素的含量变化,并进行比较分析。结果:治疗后,两组患者BMI及血清胰岛素、胰岛素抗体及瘦素含量均较治疗前明显下降(P<0.01或P<0.05);男性患者BMI及血清胰岛素含量较女性患者降低明显(均P<0.01);女性患者血清瘦素含量较男性患者降低明显(P<0.01)。结论:电针对男女单纯性肥胖症患者BMI及紊乱的胰岛素内分泌系统有明显的调节作用,但存在一定的性别差异。在降低BMI及血清胰岛素方面,男性优于女性;在减低血清瘦素方面,女性优于男性。
基金
supported by Science and Technology Support Project of Hebei Provincial Administration of Traditional Chinese Medicine,No.2014015,No.2017004
Youth Fund Project of Hebei University of Chinese Medicine,No.QNZ2014023
Science and Technology Plan Project of Hebei Provincial Department of Science and Technology,No.16277704D
Science and Technology Research Project of Universities in Hebei Province,No.QN2015139~~
